Circulating myomiRs: a new class of biomarkers to monitor skeletal muscle in physiology and medicine

J Siracusa, N Koulmann… - Journal of cachexia …, 2018 - Wiley Online Library
MicroRNAs (miRNA) are small non‐coding RNAs that target mRNAs and are consequently
involved in the post‐transcriptional regulation of gene expression. Some miRNAs are …

Smartphone-based mobile digital PCR device for DNA quantitative analysis with high accuracy

T Gou, J Hu, W Wu, X Ding, S Zhou, W Fang… - Biosensors and …, 2018 - Elsevier
Digital polymerase chain reaction (dPCR) circumventing the external calibration and
potentially providing absolute quantification of nucleic acids has become an increasingly …

Multiplexed identification, quantification and genotyping of infectious agents using a semiconductor biochip

A Hassibi, A Manickam, R Singh, S Bolouki… - Nature …, 2018 - nature.com
The emergence of pathogens resistant to existing antimicrobial drugs is a growing
worldwide health crisis that threatens a return to the pre-antibiotic era. To decrease the …

High-performance microcalorimeters: Design, applications and future development

J Feng, V Svatoš, X Liu, H Chang, P Neužil - TrAC Trends in Analytical …, 2018 - Elsevier
Microcalorimetry has been widely used to measure and characterize the heat change in
phase transition, resolution mixing, and chemical/biochemical reactions. In this review, we …

Methods for fast nucleic acid amplification

CT Wittwer, SJ Farrar - US Patent 9,932,634, 2018 - Google Patents
US9932634B2 - Methods for fast nucleic acid amplification - Google Patents US9932634B2 -
Methods for fast nucleic acid amplification - Google Patents Methods for fast nucleic acid …

Modelling DNA extension and fragmentation in contractive microfluidic devices: a Brownian dynamics and computational fluid dynamics approach

S Wu, C Li, Q Zheng, L Xu - Soft Matter, 2018 - pubs.rsc.org
Fragmenting DNA into short pieces is an essential manipulation in many biological studies,
ranging from genome sequencing to molecular diagnosis. Among various DNA …

Electrowetting-on-dielectric chip with integrated screen-printed electrochemical sensor for rapid chemical analysis

K Ugsornrat, T Maturos, P Pasakon, C Karuwan… - Materials Science and …, 2018 - Elsevier
In this work, a screen-printed electrochemical detector was fabricated on a digital
electrowetting-on-dielectric (EWOD) microfluidic chip for the first time and employed for rapid …

Rapid multiplex nucleic acid amplification test developed using paper chromatography chip and azobenzene-modified oligonucleotides

S Sano, S Miyamoto, S Kawamoto - Journal of bioscience and …, 2018 - Elsevier
Although nucleic acid amplification test (NAT) is widely used for pathogen detection, rapid
NAT systems that do not require special and expensive instruments must be developed in …

Methods and compositions for rapid thermal cycling

NR Beer, WJ Benett, JM Frank, JR Deotte… - US Patent …, 2018 - Google Patents
The rapid thermal cycling of a material is targeted. A microfluidic heat exchanger with an
internal porous medium is coupled to tanks containing cold fluid and hot fluid. Fluid flows …

[图书][B] Universal point of care biosensor using ultrafast plasmonic polymerase chain reaction

NAM Tran - 2018 - search.proquest.com
This thesis gives an overview of polymerase chain reaction (PCR) and where PCR is
currently used in research and the industry. The thesis discusses the specific components …