Objective: This systematic review summarizes the published incidence of off-label
medication use in children from the past 10 years. We also performed a retrospective chart …

Background In the past two decades, many legislative and regulatory initiatives were taken
globally to improve drug use in children. However, children are still found to be prescribed …

Objectives There is no licensed, dose‐appropriate formulation of hydrocortisone for children
with adrenal insufficiency (AI) and patients rely on compounded adult medication. The aim of …

Background The aim of this study was to explore the use of off-label/unlicensed drugs to
confirm the safety and efficacy of their prescription in children in Korea. Methods In this …

Aims of this survey were to evaluate prescription patterns for children and adolescents in
primary and hospital care settings in Austria and to identify the medicines used most …

Aims This study investigates paediatric drug dosage guidelines with the aim of investigating
their agreement with body surface area (BSA) scaling principles. Methods A total of 454 drug …

目的: 对我院2015 年眼科住院患者超说明书用药现状及其影响因素进行回顾性调查,
促进眼科临床合理用药. 方法: 从我院9 个临床科室随机抽取2015 年住院病历各100 份, 共计900 …

Hingga saat ini pengujian klinis pada populasi pediatrik masih terbilang sedikit
dibandingkan dengan pengujian klinis pada populasi dewasa. Hal ini berdampak pada …

Regulatory and subsidy approvals for medicines rely heavily on outcomes from randomised
controlled trials. However, as an evidence base for safety assessment, trials data are …

The phrase “off-label prescribing” refers to the use of medicines in ways that have not been
approved by regulatory agencies. While off-label prescribing is ubiquitous, it has been a …