Achieving controlled biomolecule–biomaterial conjugation

CD Spicer, ET Pashuck, MM Stevens - Chemical reviews, 2018 - ACS Publications
The conjugation of biomolecules can impart materials with the bioactivity necessary to
modulate specific cell behaviors. While the biological roles of particular polypeptide …

Bioorthogonal strategies for engineering extracellular matrices

CM Madl, SC Heilshorn - Advanced Functional Materials, 2018 - Wiley Online Library
Hydrogels are commonly used as engineered extracellular matrix (ECM) mimics in
applications ranging from tissue engineering to in vitro disease models. Ideal mechanisms …

Photo-crosslinkable, injectable sericin hydrogel as 3D biomimetic extracellular matrix for minimally invasive repairing cartilage

C Qi, J Liu, Y Jin, L Xu, G Wang, Z Wang, L Wang - Biomaterials, 2018 - Elsevier
Millions of patients worldwide suffer from cartilage injury and age/disease-related cartilage
degeneration. However, cartilage, such as articular cartilage, is poor at self-regeneration …

[HTML][HTML] Synthesis of bioinspired collagen/alginate/fibrin based hydrogels for soft tissue engineering

G Montalbano, S Toumpaniari, A Popov, P Duan… - Materials science and …, 2018 - Elsevier
Hydrogels based on natural polymers offer a range of properties to mimic the native
extracellular matrix, and provide microenvironments to preserve cellular function and …

Encapsulation of biological agents in hydrogels for therapeutic applications

VH Pérez-Luna, O González-Reynoso - Gels, 2018 - mdpi.com
Hydrogels are materials specially suited for encapsulation of biological elements. Their
large water content provides an environment compatible with most biological molecules …

Tuning bulk hydrogel degradation by simultaneous control of proteolytic cleavage kinetics and hydrogel network architecture

CM Madl, LM Katz, SC Heilshorn - ACS macro letters, 2018 - ACS Publications
Degradation of three-dimensional hydrogels is known to regulate many cellular behaviors.
Accordingly, several elegant approaches have been used to render hydrogels degradable …

Engineering hydrogel microenvironments to recapitulate the stem cell niche

CM Madl, SC Heilshorn - Annual review of biomedical …, 2018 - annualreviews.org
Stem cells are a powerful resource for many applications including regenerative medicine,
patient-specific disease modeling, and toxicology screening. However, eliciting the desired …

[图书][B] 3D and 4D printing in biomedical applications: process engineering and additive manufacturing

M Maniruzzaman - 2018 - books.google.com
A professional guide to 3D and 4D printing technology in the biomedical and
pharmaceutical fields 3D and 4D Printing in Biomedical Applications offers an authoritative …

Recent progress in developing injectable matrices for enhancing cell delivery and tissue regeneration

X Tong, F Yang - Advanced healthcare materials, 2018 - Wiley Online Library
Biomaterials are key factors in regenerative medicine. Matrices used for cell delivery are
especially important, as they provide support to transplanted cells that is essential for …

Synthetic hydrogels formed by thiol–ene crosslinking of vinyl sulfone-functional poly (methyl vinyl ether-alt-maleic acid) with α, ω-dithio-polyethyleneglycol

SA Stewart, MB Coulson, C Zhou, NAD Burke… - Soft Matter, 2018 - pubs.rsc.org
Polymer hydrogels formed by rapid thiol–ene coupling of macromolecular gel formers can
offer access to versatile new matrices. This paper describes the efficient synthesis of …