Accumulating evidence reveal important applications of endogenous pain modulation
assessment in healthy controls and in patients in clinical settings, as dysregulations in the …

C-low-threshold mechanoreceptors (C-LTMRs) are sensory neurons that, beyond conveying
pleasant touch, modulate nociceptive transmission within the spinal cord. However, pain …

A growing number of studies reported that rosiglitazone (a PPARgamma agonist) could
ameliorate the painful state and prevent stress-induced depression. However, whether …

Introduction: Numerous research groups have developed GlyT-1 inhibitors in the pursuit of
providing a novel antipsychotic treatment for schizophrenia. Despite multiple compounds …

Neuroplasticity in the dorsal horn after peripheral nerve damage contributes critically to the
establishment of chronic pain. The neurosecretory protein VGF (nonacronymic) is rapidly …

Spinal manipulative therapy, including low-velocity variable-amplitude spinal manipulation
(LVVA-SM), relieves chronic low back pain, especially in patients with neuropathic radiating …

Atomoxetine is a selective noradrenaline reuptake inhibitor drug. Based on the knowledge
that agents increasing monoamine levels in the central nervous system have therapeutic …

Context: Dysfunction of pain circuitry may alter normal pain perception, leading to
neuropathic pain. The underlying mechanisms are still unclear, although several animal …

Selektif noradrenalin geri alım inhibitörü bir ilaç olan atomoksetin, dikkat eksikliği
hiperaktivite bozukluğunun tedavisinde endikedir. Beyinde monoamin konsantrasyonunu …