Poxvirus-based vector systems and the potential for multi-valent and multi-pathogen vaccines

NA Prow, R Jimenez Martinez, JD Hayball… - Expert review of …, 2018 - Taylor & Francis
Introduction: With the increasing number of vaccines and vaccine-preventable diseases, the
pressure to generate multi-valent and multi-pathogen vaccines grows. Combining individual …

Aedes anphevirus: an insect-specific virus distributed worldwide in Aedes aegypti mosquitoes that has complex interplays with Wolbachia and dengue virus infection …

R Parry, S Asgari - Journal of Virology, 2018 - Am Soc Microbiol
Insect-specific viruses (ISVs) of the yellow fever mosquito Aedes aegypti have been
demonstrated to modulate transmission of arboviruses such as dengue virus (DENV) and …

[HTML][HTML] Metagenomic Analysis of Flaviviridae in Mosquito Viromes Isolated From Yunnan Province in China Reveals Genes From Dengue and Zika Viruses

P Xiao, J Han, Y Zhang, C Li, X Guo, S Wen… - Frontiers in cellular …, 2018 - frontiersin.org
More than 6,000 mosquitoes of six species from six sites were collected and tested for their
virome using metagenomics sequencing and bioinformatic analysis. The identified viral …

[HTML][HTML] Discovery and high prevalence of Phasi Charoen-like virus in field-captured Aedes aegypti in South China

X Zhang, S Huang, T Jin, P Lin, Y Huang, C Wu… - Virology, 2018 - Elsevier
Arboviruses have caused significant global health concerns during the past decade. In this
regard, continuous viral surveillance is essential to timely identify emerging arboviruses and …

[HTML][HTML] Metagenomic sequencing from mosquitoes in China reveals a variety of insect and human viruses

P Xiao, C Li, Y Zhang, J Han, X Guo, L Xie… - Frontiers in cellular …, 2018 - frontiersin.org
We collected 8,700 mosquitoes in three sites in China, which belonged to seven species.
Their viromes were tested using metagenomic sequencing and bioinformatic analysis. The …

Complete genome of Aedes aegypti anphevirus in the Aag2 mosquito cell line

F Di Giallonardo, MD Audsley, M Shi… - Journal of General …, 2018 - microbiologyresearch.org
A novel negative-sense RNA virus, Aedes aegypti anphevirus, was recently identified in wild
Aedes aegypti mosquitoes. We show that this virus is also present in the Aag2 Aedes …

Detection of a novel insect specific flavivirus across ecologically diverse populations of Aedes aegypti on the Caribbean Island of Saint Lucia

CL Jeffries, M White, L Wilson, L Yakob, T Walker - bioRxiv, 2018 - biorxiv.org
Outbreaks of mosquito-borne arboviral diseases including dengue virus (DENV), Zika virus
(ZIKV), yellow fever virus (YFV) and chikungunya virus (CHIKV) have recently occurred in …

Density dependent enhancement effect of Wolbachia and the host RNAi response to a densovirus in Aedes cells

R Parry, C Bishop, L Hayr, S Asgari - bioRxiv, 2018 - biorxiv.org
The endosymbiotic bacterium Wolbachia pipientis has been shown to restrict a range of
RNA viruses in Drosophila melanogaster and transinfected dengue mosquito, Aedes …