The term inflammatory bowel disease (IBD) refers principally to two major categories of
chronic relapsing inflammatory intestinal disorders: Crohn's disease (CD) and ulcerative …

Clinical studies demonstrate that buprenorphine is a pharmacologic agent that can be used
for the treatment of various types of painful conditions. This study investigated the efficacy of …

Importance Expanding Medicaid eligibility could affect prescriptions of buprenorphine with
naloxone, an established treatment for opioid use disorder, and opioid pain relievers …

Background: Persistence with medication-assisted therapy among patients with opioid use
disorder has been associated with reduced likelihood of illicit opioid use. Objective: We …

Objective: Posttraumatic stress disorder (PTSD) and opioid use disorder (OUD) co-occur at
high rates, and this co-occurrence is associated with a range of problems related to mental …

Receptor theory predicts that fixed-proportion mixtures of a competitive, reversible agonist
(eg, fentanyl) and antagonist (eg, naltrexone) at a common receptor [eg, mu-opioid receptors …

With the growing public health problem of opioid misuse, addiction, and overdose, the
number of patients presenting for surgery and anesthesia who may be opioid-dependent or …

Derived from thebaine, an alkaloid found in the Papaver somniferum plant, buprenorphine is
a semisynthetic, centrally acting, partial agonist for the opioid receptor. It is used clinically as …

The prevalence of substance use disorders in patients with chronic pain is higher than in the
general population. The causes and onset of substance use disorders have been difficult to …

August 2018• Volume 127• Number 2 www. anesthesia-analgesia. org 337 aim to address
whether buprenorphine is indeed safer than potential alternatives. Because serious adverse …