Vascular smooth muscle contraction in hypertension
Hypertension is a major risk factor for many common chronic diseases, such as heart failure,
myocardial infarction, stroke, vascular dementia, and chronic kidney disease …
myocardial infarction, stroke, vascular dementia, and chronic kidney disease …
Clinical relevance of aortic stiffness in end-stage renal disease and diabetes: implication for hypertension management
A Yannoutsos, SA Bahous, ME Safar… - Journal of …, 2018 - journals.lww.com
Evidence suggests that aortic stiffness may antedate and contribute initially to the
development of hypertension and cardiovascular risk (CVR). In treated hypertensive …
development of hypertension and cardiovascular risk (CVR). In treated hypertensive …
Reliability of docking-based virtual screening for GPCR ligands with homology modeled structures: A case study of the angiotensin II type I receptor
H Chen, W Fu, Z Wang, X Wang, T Lei… - ACS Chemical …, 2018 - ACS Publications
The number of solved G-protein-coupled receptor (GPCR) crystal structures has expanded
rapidly, but most GPCR structures remain unsolved. Therefore, computational techniques …
rapidly, but most GPCR structures remain unsolved. Therefore, computational techniques …
[HTML][HTML] Angiotensin II upregulates cyclophilin A by enhancing ROS production in rat cardiomyocytes
H Tian, D Yu, Y Hu, P Zhang… - Molecular …, 2018 - spandidos-publications.com
Abstract Angiotensin II (Ang II) is a principal molecule of the renin‑angiotensin system, which
promotes hypertrophy and fibrosis. It has been demonstrated that Ang II upregulates the …
promotes hypertrophy and fibrosis. It has been demonstrated that Ang II upregulates the …
CX3CL1/CX3CR1 axis contributes to angiotensin II-induced vascular smooth muscle cell proliferation and inflammatory cytokine production
C Li, J He, X Zhong, H Gan, Y Xia - Inflammation, 2018 - Springer
Abstract Angiotensin II (Ang II) dysregulation has been determined in many diseases. The
CX3CL1/CX3CR1 axis, which has a key role in cardiovascular diseases, is involved in the …
CX3CL1/CX3CR1 axis, which has a key role in cardiovascular diseases, is involved in the …
Rapamycin treatment attenuates angiotensin II-induced abdominal aortic aneurysm formation via VSMC phenotypic modulation and down-regulation of ERK1/2 …
F Li, X Shang, X Du, S Chen - Current Medical Science, 2018 - Springer
The aim of the present study is to address the effect of rapamycin on abdominal aortic
aneurysm (AAA) and the potential mechanisms. A clinically relevant AAA model was …
aneurysm (AAA) and the potential mechanisms. A clinically relevant AAA model was …
[PDF][PDF] 维持性血液透析患者自体动静脉内瘘血管钙化的研究进展
张炜晨， 张敏敏， 王梦婧， 陈靖 - 中华肾脏病杂志, 2018 - cjn.org.cn
样, 受到众多因素的影响, 比如钙磷代谢紊乱, 炎症和药物等. 但与一般的外周动脉钙化不同, AVF
因其动静脉短路的性质, 受到明显的局部血流因素的影响. 由于受到诸多全身及局部因素的影响 …
因其动静脉短路的性质, 受到明显的局部血流因素的影响. 由于受到诸多全身及局部因素的影响 …
Tempol, a superoxide dismutase-mimetic drug, prevents chronic ischemic renal injury in two-kidney, one-clip hypertensive rats
DVQ Nunes, CA Costa, GF De Bem… - Clinical and …, 2018 - Taylor & Francis
Tempol, a superoxide dismutase-mimetic drug, has been shown to attenuate radical-
induced damage, exerting beneficial effects in the animal models of oxidative stress and …
induced damage, exerting beneficial effects in the animal models of oxidative stress and …
The Expression of MAS1, an Angiotensin (1–7) Receptor, in the Eutopic Proliferative Endometria of Endometriosis Patients
T Nakajima, F Chishima, T Nakao, C Hayashi… - Gynecologic and …, 2018 - karger.com
Background/Aim: We demonstrated that AT1 and AT2 are expressed and both pathways
balance the renin-angiotensin system in endometriosis. MAS1, a specific receptor of …
balance the renin-angiotensin system in endometriosis. MAS1, a specific receptor of …
[PDF][PDF] Avaliação dos efeitos do tratamento com sildenafil na hipertensão induzida por infusão de angiotensina II
AT Dias - core.ac.uk
RESUMO A angiotensina II (Ang II) é responsável por múltiplas ações no organismo, sendo
considerada o peptídeo efetor de uma variedade de ações fisiológicas e fisiopatológicas …
considerada o peptídeo efetor de uma variedade de ações fisiológicas e fisiopatológicas …