Practice guideline update summary: Mild cognitive impairment: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the …

RC Petersen, O Lopez, MJ Armstrong, TSD Getchius… - Neurology, 2018 - AAN Enterprises
Objective To update the 2001 American Academy of Neurology (AAN) guideline on mild
cognitive impairment (MCI). Methods The guideline panel systematically reviewed MCI …

[HTML][HTML] Alterations in brain network topology and structural-functional connectome coupling relate to cognitive impairment

J Wang, R Khosrowabadi, KK Ng, Z Hong… - Frontiers in Aging …, 2018 - frontiersin.org
According to the network-based neurodegeneration hypothesis, neurodegenerative
diseases target specific large-scale neural networks, such as the default mode network, and …

[HTML][HTML] Cerebrovascular disease influences functional and structural network connectivity in patients with amnestic mild cognitive impairment and Alzheimer's …

A Vipin, YM Loke, S Liu, S Hilal, HY Shim, X Xu… - Alzheimer's research & …, 2018 - Springer
Background Patients with amnestic mild cognitive impairment (aMCI) and Alzheimer's
disease (AD) show functional and structural connectivity alterations in the default mode …

Relationships between functional fitness and cognitive impairment in Chinese community-dwelling older adults: a cross-sectional study

M Yang, Y Guo, J Gong, M Deng, N Yang, Y Yan - BMJ open, 2018 - bmjopen.bmj.com
Objective The aim of this study was to investigate the associations between each functional
fitness (FF) domain and cognitive impairment (CI) in Chinese community-dwelling older …

[HTML][HTML] Activation of sirtuin 1 attenuates high glucose-induced neuronal apoptosis by deacetylating p53

X Shi, L Pi, S Zhou, X Li, F Min, S Wang… - Frontiers in …, 2018 - frontiersin.org
Diabetes mellitus (DM) has been proven to be a key risk factor for cognitive impairment.
Previous studies have implicated hippocampal neuronal apoptosis in diabetes-related …

Homocysteine and cerebral atrophy: the epidemiology of dementia in Singapore study

B Tan, N Venketasubramanian… - Journal of …, 2018 - content.iospress.com
Background: Plasma homocysteine levels are increasingly studied as a potential risk factor
for dementia. Elevated homocysteine levels have been linked with gray and white matter …

[HTML][HTML] Haemoglobin, magnetic resonance imaging markers and cognition: a subsample of population-based study

B Tan, N Venketasubramanian, H Vrooman… - Alzheimer's research & …, 2018 - Springer
Background Low haemoglobin is highly prevalent among the elderly and has been
associated with dementia. However, the mechanisms underlying this association with …

[HTML][HTML] A novel language-neutral Visual Cognitive Assessment Test (VCAT): validation in four Southeast Asian countries

L Lim, TP Ng, AP Ong, MP Tan, AR Cenina… - Alzheimer's research & …, 2018 - Springer
Background Cognitive screeners are imperative for early diagnosis of dementia. The Visual
Cognitive Assessment Test (VCAT) is a language-neutral, visual-based test which has …

[PDF][PDF] 新版轻度认知障碍临床指南概要

何昊, 关青, 张浩波, 罗跃嘉 - 中华诊断学电子杂志, 2018 - zhzdxzz.com
美国神经病学学会(AAN) 近期发布了新版轻度认知障碍(MCI) 临床指南, 指南专家组根据AAN
的证据分类标准, 系统回顾了MCI 的发病率, 预后和治疗方面的文献, 并提出相关建议 …

[HTML][HTML] Can Youtube® Disseminate Dementia Knowledge to Singapore Chinese?

BKP Woo - Innovations in Clinical Neuroscience, 2018 - innovationscns.com
A community-based epidemiological survey has suggested that the prevalence of cognitive
impairment and dementia is approximately 15.2 percent in Singapore Chinese.[1] While …