The epigenetic alterations of endogenous retroelements in aging

M Cardelli - Mechanisms of ageing and development, 2018 - Elsevier
Endogenous retroelements, transposons that mobilize through RNA intermediates, include
some of the most abundant repetitive sequences of the human genome, such as Alu and …

DNA tumor virus regulation of host DNA methylation and its implications for immune evasion and oncogenesis

SK Kuss-Duerkop, JA Westrich, D Pyeon - Viruses, 2018 - mdpi.com
Viruses have evolved various mechanisms to evade host immunity and ensure efficient viral
replication and persistence. Several DNA tumor viruses modulate host DNA …

Epigenetics in teleost fish: From molecular mechanisms to physiological phenotypes

C Best, H Ikert, DJ Kostyniuk, PM Craig… - … and Physiology Part B …, 2018 - Elsevier
While the field of epigenetics is increasingly recognized to contribute to the emergence of
phenotypes in mammalian research models across different developmental and …

Inorganic arsenic causes fatty liver and interacts with ethanol to cause alcoholic liver disease in zebrafish

K Bambino, C Zhang, C Austin… - Disease models & …, 2018 - journals.biologists.com
The rapid increase in fatty liver disease (FLD) incidence is attributed largely to genetic and
lifestyle factors; however, environmental toxicants are a frequently overlooked factor that can …

Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome

S Rajshekar, J Yao, PK Arnold, SG Payne, Y Zhang… - Elife, 2018 - elifesciences.org
Pericentromeric satellite repeats are enriched in 5-methylcytosine (5mC). Loss of 5mC at
these sequences is common in cancer and is a hallmark of Immunodeficiency, Centromere …

[PDF][PDF] 砂仁中化学成分及其药理作用的研究进展

李丽丽, 田文仓, 刘茵, 李永杰, 曹晓霞… - 现代生物医学 …, 2018 - biomed.cnjournals.com
砂仁中的主要成分为乙酸龙脑酯, 樟脑, 龙脑等挥发性成分, 另外非挥发性成分主要有多糖,
黄酮苷类, 有机酸类以及无机成分等. 其药理作用研究大多集中在挥发油部分 …

Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression

M Yamashita, K Inoue, N Saeki… - …, 2018 - journals.biologists.com
Transcriptional regulation can be tightly orchestrated by epigenetic regulators. Among these,
ubiquitin-like with PHD and RING finger domains 1 (Uhrf1) is reported to have diverse …

[PDF][PDF] 吉西他滨热化疗治疗肝癌的临床效果及对血清MGMT 水平的影响

王宏, 夏永寿, 加静, 张燕… - Progress in Modern …, 2018 - biomed.cnjournals.com
摘要目的: 探讨吉西他滨热化疗治疗肝癌的临床效果及对血清O6-甲基鸟嘌呤DNA
甲基转移酶(O6-methylguanine-DNA methyltransferase, MGMT) 水平的影响. 方法: 选取2014 …