Force loss in skeletal muscle exposed to eccentric contraction is often attributed to injury. We
show that EDL muscles from dystrophin-deficient mdx mice recover 65% of lost force within …

Up-regulation of the dystrophin-related gene utrophin represents a promising therapeutic
strategy for the treatment of Duchenne Muscular Dystrophy (DMD). In order to re-program …

Dystrophin deficiency in mdx mice, a model for Duchenne muscular dystrophy, leads to
muscle weakness revealed by a reduced specific maximal force as well as fragility (ie …

Deterioration of neuromuscular junction (NMJ) integrity and function is causal to muscle
atrophy and frailty, ultimately hindering quality of life and increasing the risk of death. In …

Duchenne muscular dystrophy (DMD), caused by the absence of the protein dystrophin, is
characterized as a neuromuscular disease in which muscle weakness, increased …

New Findings What is the central question of this study? We examined whether the
macrophage‐synthesized antioxidant 7, 8‐dihydroneopterin was elevated in Duchenne …

Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is an autosomal
recessive motor neuron disease causing distal limb muscle atrophy that progresses …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease
characterized by chorea, incoordination and psychiatric and behavioral symptoms. The …

Skeletal muscle fibers have been used to examine a variety of cellular functions and
pathologies. Among other parameters, skeletal muscle action potential (AP) propagation has …

Cellular therapy is being actively pursued as a therapeutic modality in many of the
neurological diseases. A variety of stem cells from diverse sources have been studied in …