[HTML][HTML] Parasite recognition and signaling mechanisms in innate immune responses to malaria

DC Gowda, X Wu - Frontiers in immunology, 2018 - frontiersin.org
Malaria caused by the Plasmodium family of parasites, especially P. falciparum and P. vivax,
is a major health problem in many countries in the tropical and subtropical regions of the …

[HTML][HTML] Plasmodium vivax in vitro continuous culture: the spoke in the wheel

M Bermúdez, DA Moreno-Pérez, G Arévalo-Pinzón… - Malaria journal, 2018 - Springer
Understanding the life cycle of Plasmodium vivax is fundamental for developing strategies
aimed at controlling and eliminating this parasitic species. Although advances in omic …

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

HJ Lee, A Georgiadou, M Walther… - Science translational …, 2018 - science.org
The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In
Plasmodium falciparum malaria, host and parasite processes can be assessed by dual RNA …

[HTML][HTML] A specific PfEMP1 is expressed in P. falciparum sporozoites and plays a role in hepatocyte infection

G Zanghì, SS Vembar, S Baumgarten, S Ding… - Cell reports, 2018 - cell.com
Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and
transmission of the malaria parasite Plasmodium falciparum during blood stage infection …

Transcriptomic studies of malaria: a paradigm for investigation of systemic host-pathogen interactions

HJ Lee, A Georgiadou, TD Otto, M Levin… - Microbiology and …, 2018 - Am Soc Microbiol
Transcriptomics, the analysis of genome-wide RNA expression, is a common approach to
investigate host and pathogen processes in infectious diseases. Technical and bioinformatic …

Epigenetic variation and regulation in malaria parasites

MT Duraisingh, KM Skillman - Annual review of microbiology, 2018 - annualreviews.org
Eukaryotic pathogens must survive in different hosts, respond to changing environments,
and exploit specialized niches to propagate. Plasmodium parasites cause human malaria …

Endothelial cell protein C receptor-dependent signaling

UR Pendurthi, LVM Rao - Current opinion in hematology, 2018 - journals.lww.com
Endothelial cell protein C receptor-dependent signaling : Current Opinion in Hematology
Endothelial cell protein C receptor-dependent signaling : Current Opinion in Hematology Log …

[HTML][HTML] The Gerbich blood group system: old knowledge, new importance

E Jaskiewicz, T Peyrard, R Kaczmarek, A Zerka… - Transfusion medicine …, 2018 - Elsevier
Antigens of the Gerbich blood group system are expressed on glycophorin C (GPC) and
glycophorin D (GPD), minor sialoglycoproteins of human erythrocytes. GPC and GPD help …

Analysis of recombinational switching at the antigenic variation locus of the Lyme spirochete using a novel PacBio sequencing pipeline

TB Verhey, M Castellanos… - Molecular …, 2018 - Wiley Online Library
The Lyme disease spirochete evades the host immune system by combinatorial variation of
VlsE, a surface antigen. Antigenic variation occurs via segmental gene conversion from …

A bite to fight: front-line innate immune defenses against malaria parasites

S Tannous, E Ghanem - Pathogens and global health, 2018 - Taylor & Francis
Malaria infection caused by Plasmodium parasites remains a major health burden
worldwide especially in the tropics and subtropics. Plasmodium exhibits a complex life cycle …