Development and regulation of single- and multi-species Candida albicans biofilms

MB Lohse, M Gulati, AD Johnson… - Nature Reviews …, 2018 - nature.com
Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

Nanotechnology-based drug delivery systems for control of microbial biofilms: a review

MA Dos Santos Ramos, PB Da Silva… - International journal …, 2018 - Taylor & Francis
Since the dawn of civilization, it has been understood that pathogenic microorganisms
cause infectious conditions in humans, which at times, may prove fatal. Among the different …

[HTML][HTML] Antimicrobial activities and mechanisms of magnesium oxide nanoparticles (nMgO) against pathogenic bacteria, yeasts, and biofilms

NYT Nguyen, N Grelling, CL Wetteland, R Rosario… - Scientific reports, 2018 - nature.com
Magnesium oxide nanoparticle (nMgO) is a light metal based antimicrobial nanoparticle that
can be metabolized and fully resorbed in the body. To take advantage of the antimicrobial …

A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans

RS Shapiro, A Chavez, CBM Porter, M Hamblin… - Nature …, 2018 - nature.com
Candida albicans is the leading cause of fungal infections; yet, complex genetic interaction
analysis remains cumbersome in this diploid pathogen. Here, we developed a CRISPR …

[HTML][HTML] The interface between fungal biofilms and innate immunity

JF Kernien, BD Snarr, DC Sheppard… - Frontiers in …, 2018 - frontiersin.org
Fungal biofilms are communities of adherent cells surrounded by an extracellular matrix.
These biofilms are commonly found during infection caused by a variety of fungal …

Bacterial-derived exopolysaccharides enhance antifungal drug tolerance in a cross-kingdom oral biofilm

D Kim, Y Liu, RI Benhamou, H Sanchez… - The ISME …, 2018 - academic.oup.com
Fungal–bacterial interactions generate unique biofilms that cause many infections in
humans. Candida albicans interact with Streptococcus mutans in dental biofilms associated …

aBiofilm: a resource of anti-biofilm agents and their potential implications in targeting antibiotic drug resistance

A Rajput, A Thakur, S Sharma… - Nucleic acids research, 2018 - academic.oup.com
Biofilms play an important role in the antibiotic drug resistance, which is threatening public
health globally. Almost, all microbes mimic multicellular lifestyle to form biofilm by …

[HTML][HTML] Efflux pump-mediated resistance to antifungal compounds can be prevented by conjugation with triphenylphosphonium cation

W Chang, J Liu, M Zhang, H Shi, S Zheng, X Jin… - Nature …, 2018 - nature.com
Antifungal resistance due to upregulation of efflux pumps is prevalent in clinical Candida
isolates. Potential efflux pump substrates (PEPSs), which are active against strains deficient …

Continuous citric acid production in repeated-fed batch fermentation by Aspergillus niger immobilized on a new porous foam

B Yu, X Zhang, W Sun, X Xi, N Zhao, Z Huang… - Journal of …, 2018 - Elsevier
The efficiency of current methods for industrial production of citric acid is limited. To achieve
continuous citric acid production with enhanced yield and reduced cost, immobilized …

[HTML][HTML] Synergistic interactions in microbial biofilms facilitate the establishment of opportunistic pathogenic fungi in household dishwashers

J Zupančič, PK Raghupathi, K Houf… - Frontiers in …, 2018 - frontiersin.org
Biofilms formed on rubber seals in dishwashers harbor diverse microbiota. In this study, we
focussed on the microbial composition of bacteria and fungi, isolated from a defined area of …