3D and 4D bioprinting of the myocardium: current approaches, challenges, and future prospects

CS Ong, L Nam, K Ong, A Krishnan… - BioMed research …, 2018 - Wiley Online Library
3D and 4D bioprinting of the heart are exciting notions in the modern era. However,
myocardial bioprinting has proven to be challenging. This review outlines the methods …

Integrated approaches to spatiotemporally directing angiogenesis in host and engineered tissues

RJ Kant, KLK Coulombe - Acta biomaterialia, 2018 - Elsevier
The field of tissue engineering has turned towards biomimicry to solve the problem of tissue
oxygenation and nutrient/waste exchange through the development of vasculature …

Tissue engineering: Still facing a long way ahead

P Hassanzadeh, F Atyabi, R Dinarvand - Journal of Controlled Release, 2018 - Elsevier
Tissue engineering (TE) has provided promising perspectives to overcome the limited
efficiency of the conventional treatment options or organ transplantation. Considerable …

The arteriovenous loop: engineering of axially vascularized tissue

A Weigand, RE Horch, AM Boos, JP Beier… - European Surgical …, 2018 - karger.com
Background: Most of the current treatment options for large-scale tissue defects represent a
serious burden for the patients, are often not satisfying, and can be associated with …

The vascularised chamber as an in vivo bioreactor

KK Yap, GC Yeoh, WA Morrison, GM Mitchell - Trends in biotechnology, 2018 - cell.com
Vascularisation is key to developing large transplantable tissue constructs capable of
providing therapeutic benefits. The vascularised tissue engineering chamber originates from …

Micro-RNA–Regulated Proangiogenic Signaling in Arteriovenous Loops in Patients with Combined Vascular and Soft-Tissue Reconstructions: Revisiting the Nutrient …

D Henn, M Abu-Halima, F Falkner… - Plastic and …, 2018 - journals.lww.com
Background: The placement of arteriovenous loops can enable microvascular anastomoses
of free flaps when recipient vessels are scarce. In animal models, elevated fluid shear stress …

Engineering a microcirculation for perfusion control of ex vivo–assembled organ systems: Challenges and opportunities

P Kottamasu, I Herman - Journal of Tissue Engineering, 2018 - journals.sagepub.com
Donor organ shortage remains a clear problem for many end-stage organ patients around
the world. The number of available donor organs pales in comparison with the number of …

Effects of platelet-rich plasma on tissue-engineered vascularized flaps in an in vivo chamber

Y Tanaka, Y Hamamoto, A Niyazi, T Nagasao… - Journal of Plastic …, 2018 - Elsevier
Aims We investigated the reproducibility of creating a vascularized tissue flap in an in vivo
tissue engineering chamber by incubating a vascular pedicle imbedded in a collagen …

A novel microsurgical rodent model for the transplantation of engineered cardiac muscle flap

R Tee, WA Morrison, RJ Dilley - Microsurgery, 2018 - Wiley Online Library
Background The survival of engineered cardiac muscle 'grafts' to the epicardium is limited by
vascularization post‐transplantation in rat models. In this article, we describe the …

[PDF][PDF] Grant number: 509271

R Tee - minerva-access.unimelb.edu.au
Background: The survival of engineered cardiac muscle 'grafts' to the epicardium is limited
by vascularization post-transplantation in rat models. In this paper we describe the …