An outstanding characteristic of gliomas is their infiltration into brain parenchyma, a property
that impairs complete surgical resection; consequently, these tumors might recur, resulting in …

Introduction: Tumor-derived exosomes (TEX) and their role in tumor progression by
accelerating angiogenesis are of great current interest. A better understanding of the …

For solid tumors, such as head and neck squamous cell carcinoma (HNSCC), an adequate
blood supply is of critical importance for tumor development and metastasis. Tumor-derived …

Glioblastoma multiforme (GBM) is a devastating tumour with abysmal prognoses. We
desperately need novel approaches to understand GBM biology and therapeutic …

The role of extracellular vesicles in cancer biology has emerged as a focus of the study of
great importance and has been shown to directly influence tumour development in several …

Extracellular vesicles (EVs) are membrane vesicles that are released from cells and mediate
cell–cell communication. EVs carry protein, lipid, and nucleic acid cargoes that interact with …

The proangiogenic cytokine Interleukin-3 (IL-3) is released by inflammatory cells in breast
and ovarian cancer tissue microenvironments and also acts as an autocrine factor for human …

Angiogenesis is crucial for tumor growth and metastasis. Recent studies revealed that tumor
cells promote angiogenesis by secreting extracellular vesicles, which can be captured by …

Background We have previously identified tissue inhibitor of metalloproteinases-1 (TIMP-1)
as a prognostic marker in glioblastomas. TIMP-1 has been associated with chemotherapy …

外泌体(exosomes) 是一种体内多种细胞可以分泌的细胞外囊泡, 由膜蛋白组成的脂质双分子层
包绕蛋白质和核酸形成, 其直径大小为30~ 100nm 不等. 其内含有microRNAs (miRNAs) …