Background Exercise effects in cancer patients often appear modest, possibly because
interventions rarely target patients most in need. This study investigated the moderator …

Aims and objectives To summarise the current state of knowledge of symptom clusters
research from studies that included, as part of their sample, patients who were receiving …

Longitudinal Trajectory and Characterization of Cancer-Related Cognitive Impairment in a
Nationwide Cohort Study - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Preclinical data support a role for the IL-6/JAK2/STAT3 signaling pathway in breast cancer.
Ruxolitinib is an orally bioavailable receptor tyrosine inhibitor targeting JAK1 and JAK2. We …

Context Symptom researchers have proposed a model of inflammatory cytokine activity and
dysregulation in cancer to explain co-occurring symptoms including pain, fatigue, and sleep …

Purpose Breast cancer is the leading cause of cancer mortality in women worldwide. With
medical advances, metastatic breast cancer (MBC) patients often live for years with many …

Abstract The US Food and Drug Administration and the Critical Path Institute's Patient-
Reported Outcome (PRO) Consortium convened a cosponsored workshop on the use of …

Objective Patients receiving treatment for advanced cancer suffer significant symptom
burden, including co‐occurring pain, fatigue, and sleep disturbance. There is limited …

Background Cancer-related cognitive impairment (CRCI) is often related to chemotherapy.
Increased chronic inflammation is believed to play a key role in the development of CRCI …

Background: Despite advances in cancer disease prevention, diagnosis, and treatment
patients with cancer suffer from a variety of sometimes severe physical and psychological …