[HTML][HTML] Medullary thyroid carcinoma beyond surgery: advances, challenges, and perspectives

L Ceolin, MA da Silveira Duval… - Endocrine-related …, 2019 - erc.bioscientifica.com
Medullary thyroid carcinoma (MTC) is a rare type of tumor that originates from thyroid C cells
and accounts for 2–4% of all malignant thyroid neoplasms. MTC may occur sporadically or …

[HTML][HTML] Molecular alterations in thyroid cancer: from bench to clinical practice

E Tirrò, F Martorana, C Romano, SR Vitale, G Motta… - Genes, 2019 - mdpi.com
Thyroid cancer comprises different clinical and histological entities. Whereas differentiated
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …

Survival and long-term biochemical cure in medullary thyroid carcinoma in Denmark 1997–2014: a nationwide study

JS Mathiesen, JP Kroustrup, P Vestergaard… - Thyroid, 2019 - liebertpub.com
Background: Survival of medullary thyroid carcinoma (MTC) subgroups in relation to the
general population is poorly described. Data on the factors predicting long-term biochemical …

LncRNA FOXD2‐AS1 accelerates the papillary thyroid cancer progression through regulating the miR‐485‐5p/KLK7 axis

Y Zhang, J Hu, W Zhou, H Gao - Journal of cellular biochemistry, 2019 - Wiley Online Library
It has been proved that long noncoding RNAs (lncRNAs) are important modulators in the
tumorigenesis and progression of various malignant tumors. Recently, lncRNA FOXD2‐AS1 …

Association between programmed death-ligand 1 expression and clinicopathological characteristics, structural recurrence, and biochemical recurrence/persistent …

X Shi, PC Yu, BW Lei, CW Li, Y Zhang, LC Tan, RL Shi… - Thyroid, 2019 - liebertpub.com
Background: Expression of the programmed death-ligand 1 (PD-L1) in medullary thyroid
carcinoma (MTC) has been rarely reported. In this study, we evaluated PD-L1 positivity in …

[HTML][HTML] The role of calcitonin in predicting the extent of surgery in medullary thyroid carcinoma: a nationwide population-based study in Norway

EM Opsahl, LA Akslen, E Schlichting… - European thyroid …, 2019 - etj.bioscientifica.com
Background: Preoperative predictors for the need of prophylactic lymph node dissection in
the lateral neck have been studied in patients with medullary thyroid carcinoma (MTC) …

Cure and survival of sporadic medullary thyroid carcinoma following systematic preoperative calcitonin screening

F Torresan, C Mian, E Cavedon, M Iacobone - Langenbeck's archives of …, 2019 - Springer
Background The improvement in outcome of sporadic medullary thyroid carcinoma (MTC)
during the last decades remains controversial, even if a trend toward a better prognosis has …

[HTML][HTML] Prognostic value of numbers of metastatic lymph node in medullary thyroid carcinoma: a population-based study using the SEER 18 database

K Meng, H Luo, H Chen, H Guo, W Xia - Medicine, 2019 - journals.lww.com
Lymph node (LN) metastases are widely considered as a vital assessment of disease
progression, as well as an essential indicator for biochemical cure of medullary thyroid …

[HTML][HTML] Trends in diagnostics, surgical treatment, and prognostic factors for outcomes in medullary thyroid carcinoma in Norway: a nationwide population-based study

EM Opsahl, LA Akslen, E Schlichting… - European Thyroid …, 2019 - etj.bioscientifica.com
Background: Medullary thyroid carcinoma (MTC) is rare. Nationwide population-based
studies are important to evaluate its clinical course. Objectives: To describe all patients with …

Examined and positive lymph nodes counts and lymph nodes ratio are associated with survival in major salivary gland cancer

KM Elhusseiny, FAE Abd‐Elhay, MG Kamel… - Head & …, 2019 - Wiley Online Library
Background We aimed to investigate the prognostic role of examined (dissected) lymph
nodes (ELNs), negative LNs (NLNs), and positive (metastatic) LNs (PLNs) counts and LN …