BRAF mutations and the utility of RAF and MEK inhibitors in primary brain tumors
KC Schreck, SA Grossman, CA Pratilas - Cancers, 2019 - mdpi.com
BRAF mutations have been identified as targetable, oncogenic mutations in many cancers.
Given the paucity of treatments for primary brain tumors and the poor prognosis associated …
Given the paucity of treatments for primary brain tumors and the poor prognosis associated …
Advances in the management of craniopharyngioma in children and adults
M Jensterle, S Jazbinsek, R Bosnjak… - Radiology and …, 2019 - sciendo.com
Background. Childhood and adult-onset craniopharyngioma is a rare embryogenic tumor of
the sellar, suprasellar, and parasellar region. Survival rates are high; however, tumor …
the sellar, suprasellar, and parasellar region. Survival rates are high; however, tumor …
Targeted treatment of papillary craniopharyngiomas harboring BRAF V600E mutations
TA Juratli, PS Jones, N Wang, M Subramanian… - Cancer, 2019 - Wiley Online Library
Papillary craniopharyngiomas (PCPs) are characterized by the presence of BRAF V600E
mutations, which are emerging as a useful guide for diagnosis and treatment decision …
mutations, which are emerging as a useful guide for diagnosis and treatment decision …
The medical therapy of craniopharyngiomas: the way ahead
KI Alexandraki, GA Kaltsas, N Karavitaki… - The Journal of …, 2019 - academic.oup.com
Context Craniopharyngiomas, which are categorized as adamantinomatous (ACPs) or
papillary (PCPs), have traditionally been treated with surgery and/or radiotherapy, although …
papillary (PCPs), have traditionally been treated with surgery and/or radiotherapy, although …
A clinical rule for preoperative prediction of BRAF mutation status in craniopharyngiomas
S Fujio, TA Juratli, K Arita, H Hirano, Y Nagano… - …, 2019 - journals.lww.com
BACKGROUND Papillary craniopharyngiomas are characterized by BRAF V600E
mutations. Targeted therapy can elicit a dramatic radiographic regression of these tumors …
mutations. Targeted therapy can elicit a dramatic radiographic regression of these tumors …
[HTML][HTML] Newly diagnosed papillary craniopharyngioma with BRAF V600E mutation treated with single-agent selective BRAF inhibitor dabrafenib: a case report
M Rao, M Bhattacharjee, S Shepard, S Hsu - Oncotarget, 2019 - ncbi.nlm.nih.gov
We report a case of a patient with newly diagnosed, locally extensive and cystic, suprasellar
papillary craniopharyngioma successfully treated with single-agent Dabrafenib. The patient …
papillary craniopharyngioma successfully treated with single-agent Dabrafenib. The patient …
Papillary craniopharyngioma in a 4-year-old girl with BRAF V600E mutation: a case report and review of the literature
R Borrill, E Cheesman, S Stivaros, ID Kamaly-Asl… - Child's Nervous …, 2019 - Springer
Introduction Craniopharyngiomas are one of the most frequently diagnosed hypothalamo-
pituitary tumors in childhood. The adamantinomatous histological subtype accounts for most …
pituitary tumors in childhood. The adamantinomatous histological subtype accounts for most …
Craniopharyngiomas and odontogenic tumors mimic normal odontogenesis and share genetic mutations, histopathologic features, and molecular pathways activation
Odontogenic tumors bear some histopathologic and molecular resemblance to
craniopharyngiomas. Specifically, adamantinomatous craniopharyngioma shares …
craniopharyngiomas. Specifically, adamantinomatous craniopharyngioma shares …
Adjuncts in glial tumor management: Optimizing strategy
D Muzumdar - International Journal of Neurooncology, 2019 - journals.lww.com
Surgery for low‑and high‑grade gliomas has evolved over the last two to three decades and
is still in evolution to achieve maximum resection rate. With the advances in radiation …
is still in evolution to achieve maximum resection rate. With the advances in radiation …
Überblick der Versorgungssituation von erwachsenen Kraniopharyngeom-Patienten in Deutschland
TK Kellner - 2019 - ediss.sub.uni-hamburg.de
Das Kraniopharyngeom ist ein seltener Tumor des zentralen Nervensystems, der
überwiegend im Kindesalter auftritt und in dieser Altersgruppe bereits ausführlich …
überwiegend im Kindesalter auftritt und in dieser Altersgruppe bereits ausführlich …