[HTML][HTML] The pathogenesis of endometriosis: molecular and cell biology insights
The etiopathogenesis of endometriosis is a multifactorial process resulting in a
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …
[HTML][HTML] Durum wheat genome highlights past domestication signatures and future improvement targets
The domestication of wild emmer wheat led to the selection of modern durum wheat, grown
mainly for pasta production. We describe the 10.45 gigabase (Gb) assembly of the genome …
mainly for pasta production. We describe the 10.45 gigabase (Gb) assembly of the genome …
[HTML][HTML] YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression
Y Shi, S Fan, M Wu, Z Zuo, X Li, L Jiang, Q Shen… - Nature …, 2019 - nature.com
Hypoxia occurs naturally at high-altitudes and pathologically in hypoxic solid tumors. Here,
we report that genes involved in various human cancers evolved rapidly in Tibetans and six …
we report that genes involved in various human cancers evolved rapidly in Tibetans and six …
Comparative genetic architectures of schizophrenia in East Asian and European populations
Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk
globally. Large-scale schizophrenia genetic studies have reported primarily on European …
globally. Large-scale schizophrenia genetic studies have reported primarily on European …
[HTML][HTML] Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology
J Plassais, J Kim, BW Davis, DM Karyadi… - Nature …, 2019 - nature.com
Domestic dog breeds are characterized by an unrivaled diversity of morphologic traits and
breed-associated behaviors resulting from human selective pressures. To identify the …
breed-associated behaviors resulting from human selective pressures. To identify the …
[HTML][HTML] Hemorrhagic fever-causing arenaviruses: lethal pathogens and potent immune suppressors
Hemorrhagic fevers (HF) resulting from pathogenic arenaviral infections have traditionally
been neglected as tropical diseases primarily affecting African and South American regions …
been neglected as tropical diseases primarily affecting African and South American regions …
[图书][B] Human evolutionary genetics: origins, peoples and disease
M Jobling, C Tyler-Smith - 2019 - taylorfrancis.com
Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …
together molecular genetics and genomics to the study of the origins and movements of …
[HTML][HTML] ImaGene: a convolutional neural network to quantify natural selection from genomic data
L Torada, L Lorenzon, A Beddis, U Isildak, L Pattini… - BMC …, 2019 - Springer
Background The genetic bases of many complex phenotypes are still largely unknown,
mostly due to the polygenic nature of the traits and the small effect of each associated …
mostly due to the polygenic nature of the traits and the small effect of each associated …
Multiple modes of convergent adaptation in the spread of glyphosate-resistant Amaranthus tuberculatus
JM Kreiner, DA Giacomini, F Bemm… - Proceedings of the …, 2019 - National Acad Sciences
The selection pressure exerted by herbicides has led to the repeated evolution of herbicide
resistance in weeds. The evolution of herbicide resistance on contemporary timescales in …
resistance in weeds. The evolution of herbicide resistance on contemporary timescales in …
Population genomics: advancing understanding of nature
Population genomics is advancing our understanding of evolution, ecology, conservation,
agriculture, forestry, and human health by allowing new and long-standing questions to be …
agriculture, forestry, and human health by allowing new and long-standing questions to be …