[HTML][HTML] The pathogenesis of endometriosis: molecular and cell biology insights

AS Laganà, S Garzon, M Götte, P Viganò… - International journal of …, 2019 - mdpi.com
The etiopathogenesis of endometriosis is a multifactorial process resulting in a
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …

[HTML][HTML] Durum wheat genome highlights past domestication signatures and future improvement targets

M Maccaferri, NS Harris, SO Twardziok, RK Pasam… - Nature …, 2019 - nature.com
The domestication of wild emmer wheat led to the selection of modern durum wheat, grown
mainly for pasta production. We describe the 10.45 gigabase (Gb) assembly of the genome …

[HTML][HTML] YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression

Y Shi, S Fan, M Wu, Z Zuo, X Li, L Jiang, Q Shen… - Nature …, 2019 - nature.com
Hypoxia occurs naturally at high-altitudes and pathologically in hypoxic solid tumors. Here,
we report that genes involved in various human cancers evolved rapidly in Tibetans and six …

Comparative genetic architectures of schizophrenia in East Asian and European populations

M Lam, CY Chen, Z Li, AR Martin, J Bryois, X Ma… - Nature …, 2019 - nature.com
Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk
globally. Large-scale schizophrenia genetic studies have reported primarily on European …

[HTML][HTML] Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology

J Plassais, J Kim, BW Davis, DM Karyadi… - Nature …, 2019 - nature.com
Domestic dog breeds are characterized by an unrivaled diversity of morphologic traits and
breed-associated behaviors resulting from human selective pressures. To identify the …

[HTML][HTML] Hemorrhagic fever-causing arenaviruses: lethal pathogens and potent immune suppressors

ME Brisse, H Ly - Frontiers in immunology, 2019 - frontiersin.org
Hemorrhagic fevers (HF) resulting from pathogenic arenaviral infections have traditionally
been neglected as tropical diseases primarily affecting African and South American regions …

[图书][B] Human evolutionary genetics: origins, peoples and disease

M Jobling, C Tyler-Smith - 2019 - taylorfrancis.com
Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …

[HTML][HTML] ImaGene: a convolutional neural network to quantify natural selection from genomic data

L Torada, L Lorenzon, A Beddis, U Isildak, L Pattini… - BMC …, 2019 - Springer
Background The genetic bases of many complex phenotypes are still largely unknown,
mostly due to the polygenic nature of the traits and the small effect of each associated …

Multiple modes of convergent adaptation in the spread of glyphosate-resistant Amaranthus tuberculatus

JM Kreiner, DA Giacomini, F Bemm… - Proceedings of the …, 2019 - National Acad Sciences
The selection pressure exerted by herbicides has led to the repeated evolution of herbicide
resistance in weeds. The evolution of herbicide resistance on contemporary timescales in …

Population genomics: advancing understanding of nature

G Luikart, M Kardos, BK Hand, OP Rajora… - Population genomics …, 2019 - Springer
Population genomics is advancing our understanding of evolution, ecology, conservation,
agriculture, forestry, and human health by allowing new and long-standing questions to be …