Small GTPase peripheral binding to membranes: molecular determinants and supramolecular organization
F Peurois, G Peyroche, J Cherfils - Biochemical Society …, 2019 - portlandpress.com
Small GTPases regulate many aspects of cell logistics by alternating between an inactive,
GDP-bound form and an active, GTP-bound form. This nucleotide switch is coupled to a …
GDP-bound form and an active, GTP-bound form. This nucleotide switch is coupled to a …
A steric gating mechanism dictates the substrate specificity of a Rab-GEF
LL Thomas, SA van der Vegt, JC Fromme - Developmental cell, 2019 - cell.com
Summary Correct localization of Rab GTPases in cells is critical for proper function in
membrane trafficking, yet the mechanisms that target Rabs to specific subcellular …
membrane trafficking, yet the mechanisms that target Rabs to specific subcellular …
Multiple roles of Rab GTPases at the Golgi
C Progida - The Golgi Apparatus and Centriole: Functions …, 2019 - Springer
The Golgi apparatus is a central sorting station in the cell. It receives newly synthesized
molecules from the endoplasmic reticulum and directs them to different subcellular …
molecules from the endoplasmic reticulum and directs them to different subcellular …
Spatial cycling of rab GTPase, driven by the GTPase cycle, controls rab's subcellular distribution
Rab GTPases (> 60 members in humans) function as master regulators of intracellular
membrane trafficking. Correct and specific localization of Rab proteins is required for their …
membrane trafficking. Correct and specific localization of Rab proteins is required for their …
Recognition and stabilization of geranylgeranylated human Rab5 by the GDP Dissociation Inhibitor (GDI)
E Edler, M Stein - Small GTPases, 2019 - Taylor & Francis
ABSTRACT The small GTPase Rab5 is the key regulator of early endosomal fusion. It is post-
translationally modified by covalent attachment of two geranylgeranyl (GG) chains to …
translationally modified by covalent attachment of two geranylgeranyl (GG) chains to …
Autophagy inhibitor Vacuolin-1 interferes with lipid-based small interference RNA delivery
Autophagy and endocytosis are important pathways regulating macromolecule recycling
and regeneration. Small molecule inhibitors are utilized to modulate these pathways and to …
and regeneration. Small molecule inhibitors are utilized to modulate these pathways and to …
Guarding the Vacuole: How Legionella T4SS Substrate SdhA Maintains Vacuole Integrity
IS Anand - 2019 - search.proquest.com
Legionella pneumophila is a Gram-negative, intracellular pathogen that targets amoebal
species in aquatic environments and alveolar macrophages in humans. To sustain …
species in aquatic environments and alveolar macrophages in humans. To sustain …
[PDF][PDF] Μελέτη της χωροχρονικής οργάνωσης των RabGTPασών στη ρυθμιζόμενη έκκριση στα ενδοθηλιακά κύτταρα
Δ Γκέκα - 2019 - olympias.lib.uoi.gr
Η παρούσα διδακτορική διατριβή εκπονήθηκε την περίοδο Φεβρουάριος 2014-Ιανουάριος
2019 στο Ινστιτούτο Μοριακής Βιολογίας και Βιοτεχνολογίας (ΙΜΒΒ) του Ιδρύματος …
2019 στο Ινστιτούτο Μοριακής Βιολογίας και Βιοτεχνολογίας (ΙΜΒΒ) του Ιδρύματος …