Rethinking mechanisms, diagnosis and management of endometriosis

C Chapron, L Marcellin, B Borghese… - Nature Reviews …, 2019 - nature.com
Endometriosis is a chronic inflammatory disease defined as the presence of endometrial
tissue outside the uterus, which causes pelvic pain and infertility. This disease should be …

[HTML][HTML] Pathogenesis of endometriosis: the genetic/epigenetic theory

PR Koninckx, A Ussia, L Adamyan, A Wattiez… - Fertility and sterility, 2019 - Elsevier
Objective To study the pathophysiology of endometriosis. Design Overview of observations
on endometriosis. Setting Not applicable. Patient (s) None. Interventions (s) None. Main …

Diagnosis of endometriosis in the 21st century

L Kiesel, M Sourouni - Climacteric, 2019 - Taylor & Francis
Endometriosis is a common disease but, due to the wide spectrum of symptoms, diagnosis
can be delayed 8–12 years. Laparoscopy is nowadays the gold standard for diagnosis. A …

[HTML][HTML] Defining the genetic profile of endometriosis

L Vassilopoulou, M Matalliotakis… - Experimental and …, 2019 - spandidos-publications.com
Endometriosis is a pathological condition which has been extensively studied, since its
pathophysiology stems from a broad spectrum of environmental influences and genetic …

[HTML][HTML] Downregulated circular RNA hsa_circ_0067301 regulates epithelial-mesenchymal transition in endometriosis via the miR-141/Notch signaling pathway

M Zhang, S Wang, LU Tang, X Wang, T Zhang… - Biochemical and …, 2019 - Elsevier
Endometriosis is a common gynecologic disorder with enigmatic etiopathogenesis and is
characterized by tumor-like biological behaviors. Epithelial-mesenchymal transition (EMT) …

[HTML][HTML] Role of FN1 and GREB1 gene polymorphisms in endometriosis

C Matalliotaki, M Matalliotakis… - Molecular …, 2019 - spandidos-publications.com
Endometriosis is a complex gynecological disorder, affecting up to 10% of women of
childbearing age, characterized by the presence of functional endometrial tissue at ectopic …

Генетические и эпигенетические механизмы бесплодия, ассоциированного с генитальным эндометриозом

ОА Мелкозерова, НВ Башмакова… - Акушерство и …, 2019 - elibrary.ru
В статье проанализированы данные систематических обзоров и рандомизированных
клинических исследований, посвященных современным представлениям о патогенезе …

Whole exome sequencing identifies hemizygous deletions in the UGT2B28 and USP17L2 genes in a three‑generation family with endometriosis

HM Albertsen, C Matalliotaki… - Molecular …, 2019 - spandidos-publications.com
Endometriosis is an enigmatic condition with an unknown etiology and a poorly understood
pathogenesis. It is considered to appear from the interplay of many genetic and …

Development of a prediction model to aid primary care physicians in early identification of women at high risk of developing endometriosis: cross-sectional study

NJ Verket, RS Falk, E Qvigstad, TG Tanbo, L Sandvik - BMJ open, 2019 - bmjopen.bmj.com
Objectives To identify predictors of disease among a few factors commonly associated with
endometriosis and if successful, to combine these to develop a prediction model to aid …

Implication of VEGFR2 in endometriosis: A structural biological and genetic approach

C Matalliotaki, E Eliopoulos… - World Academy of …, 2019 - spandidos-publications.com
Vascular endothelial growth factor receptor 2 (VEGFR2) is a tyrosine kinase receptor, which
exerts its activity by binding to VEGF, a major mediator of angiogenesis. Endometriosis is …