Age-related macular degeneration (AMD) is the most common cause of blindness among
the elderly in the developed world. While treatment is effective for the neovascular or “wet” …

Data from human dry and wet age-related macular degeneration (AMD) eyes support the
hypothesis that constant 'tickover'of the alternative complement pathway results in chronic …

Motivation While large-scale whole genome sequencing is feasible the high costs compel
investigators to focus on disease subjects. As a result large sequencing datasets of samples …

Purpose Intronic variants in the placental growth factor (PGF) gene have been associated
with neovascular age-related macular degeneration (AMD). This study is to discover and …

Recent advances in genomic technologies, particularly next-generation sequencing (NGS)
methods, have brought a paradigm shift in discovering eye disease-associated genetic …

Age-related macular degeneration (AMD) is a leading cause of visual impairment in ageing
populations and has no radical treatment or prevention. Although genome-wide association …