The aggregation of fibrils of hyperphosphorylated and C-terminally truncated microtubule-
associated tau protein characterizes 80% of all dementia disorders, the most common …

Study design This is a narrative review of the literature on neurochemical biomarkers in
spinal cord injury (SCI). Objectives The objective was to summarize the literature on …

Background After traumatic brain injury (TBI), plasma concentration of glial fibrillary acidic
protein (GFAP) correlates with intracranial injury visible on CT scan. Some patients with …

Introduction Plasma tau may be an accessible biomarker for Alzheimer's disease (AD), but
the correlation between plasma and cerebrospinal fluid (CSF) tau and the value of …

Traumatic brain injury (TBI) is one of the most common causes of neurological damage in
young human populations. Vitamin B12 has been reported to promote axon growth of …

The aim of the study was to examine the ability of eight protein biomarkers and their
combinations in discriminating computed tomography (CT)-negative and CT-positive …

Awareness of the highly detrimental and long-term sequelae of brain injuries, and in
particular repetitive mild traumatic brain injuries (mTBIs/concussions), has been rapidly …

Nusinersen is the first approved drug for the treatment of spinal muscular atrophy (SMA).
Treatment of SMA with nusinersen is based on a fixed dosing regimen. For other …

Traumatic brain injury (TBI) is a risk factor for a group of neurodegenerative diseases termed
tauopathies, which includes Alzheimer's disease and chronic traumatic encephalopathy …

Background Tau stabilizes microtubules; however, in Alzheimer's disease (AD) and
tauopathies, tau becomes hyperphosphorylated, aggregates, and results in neuronal death …