ST2/IL-33 signaling in cardiac fibrosis

E Vianello, E Dozio, L Tacchini, L Frati… - The international journal …, 2019 - Elsevier
Cardiac fibrosis is a significant global health problem associated with nearly all forms of
heart disease. In the heart interstitial fibrosis may be reparative, replacing areas damaged …

IL-1 family cytokines in cardiovascular disease

S Pfeiler, H Winkels, M Kelm, N Gerdes - Cytokine, 2019 - Elsevier
Abstract The interleukin (IL)-1 family is a group of cytokines crucially involved in regulating
immune responses to infectious challenges and sterile insults. The family consists of the …

[HTML][HTML] Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis

H Gallagher, JO Williams, N Ferekidis, A Ismail… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Atherosclerosis and its complications are responsible for one in three global deaths.
Nutraceuticals show promise in the prevention and treatment of atherosclerosis but require …

The role of pro-inflammatory cytokines in lipid metabolism of metabolic diseases

Y Chen, CY Yu, WM Deng - International reviews of immunology, 2019 - Taylor & Francis
Adipose tissue has been considered as a crucial source of certain pro-inflammatory
cytokines; conversely, these pro-inflammatory cytokines are involved in regulating the …

Periodontitis is associated with elevated serum levels of cardiac biomarkers—Soluble ST2 and C‐reactive protein

K Torrungruang, D Katudat… - Journal of clinical …, 2019 - Wiley Online Library
Aim This cross‐sectional study examined the associations between periodontitis and the
serum cardiac biomarkers—soluble ST2 (sST2) and C‐reactive protein (CRP)—in …

Interleukin‐12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE‐/‐Mice

Y Huang, H Hu, L Liu, J Ye, Z Wang… - Mediators of …, 2019 - Wiley Online Library
Interleukin‐(IL‐) 35, a novel functional cytokine of regulatory T cells (Treg) comprised of the
IL‐12p35 subunit and the other subunit Epstein‐Barr virus‐induced gene 3 (EBI3), regulates …

Dual immune functions of IL-33 in inflammatory bowel disease.

J Chen, Y He, L Tu, L Duan - Histology and Histopathology, 2019 - europepmc.org
Interleukin-33 (IL-33) has emerged as a critical regulator in a variety of diseases, including
inflammatory bowel disease (IBD). IL-33 can be produced by various tissues and cells, and …

The interleukin-33-mediated inhibition of expression of two key genes implicated in atherosclerosis in human macrophages requires MAP kinase, phosphoinositide 3 …

ML Buckley, JO Williams, YH Chan, L Laubertová… - Scientific Reports, 2019 - nature.com
Atherosclerosis, a chronic inflammatory disorder of the walls of arteries, causes more deaths
worldwide than any other disease. Cytokines, which are present at high levels in …

[HTML][HTML] Molecular mechanisms regulating immune responses in thromboangiitis obliterans: A comprehensive review

A Shapouri-Moghaddam… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
Thromboangiitis obliterans (TAO) is a thrombotic-occlusive as well as an inflammatory
peripheral vascular disease with unknown etiology. Recent evidence has supported the …

[HTML][HTML] Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis

P Korhonen, E Pollari, KM Kanninen, E Savchenko… - IBRO reports, 2019 - Elsevier
Inflammation is a prominent feature of the neuropathology of amyotrophic lateral sclerosis
(ALS). Emerging evidence suggests that inflammatory cascades contributing to the disease …