[HTML][HTML] Fibroblast growth factor receptor signaling in skin cancers
M Czyz - Cells, 2019 - mdpi.com
Fibroblast growth factor (FGF)/Fibroblast growth factor receptor (FGFR) signaling regulates
various cellular processes during the embryonic development and in the adult organism. In …
various cellular processes during the embryonic development and in the adult organism. In …
FGFR2 promotes expression of PD-L1 in colorectal cancer via the JAK/STAT3 signaling pathway
P Li, T Huang, Q Zou, D Liu, Y Wang, X Tan… - The Journal of …, 2019 - journals.aai.org
Although multidisciplinary treatment is widely applied in colorectal cancer (CRC), the
prognosis of patients with advanced CRC remains poor. Immunotherapy blocking of …
prognosis of patients with advanced CRC remains poor. Immunotherapy blocking of …
Investigational fibroblast growth factor receptor 2 antagonists in early phase clinical trials to treat solid tumors
D Wang, L Yang, W Yu, Y Zhang - Expert Opinion on Investigational …, 2019 - Taylor & Francis
Introduction: Fibroblast growth factor receptor 2 (FGFR2) is a highly conserved
transmembrane tyrosine kinase receptor. FGFR2 dysregulation occurs in numerous human …
transmembrane tyrosine kinase receptor. FGFR2 dysregulation occurs in numerous human …
Gene expression profiling in aggressive digital papillary adenocarcinoma sheds light on the architecture of a rare sweat gland carcinoma
HM Surowy, AK Giesen, J Otte, R Büttner… - British Journal of …, 2019 - academic.oup.com
Background Sweat gland carcinomas are rare cutaneous adnexal malignancies. Aggressive
digital papillary adenocarcinoma (ADPA) represents a very rare subentity, thought to arise …
digital papillary adenocarcinoma (ADPA) represents a very rare subentity, thought to arise …
Caracterização biofísico-química das proteínas FGFR2 e Grb2 e sua dinâmica de interação
JA Tedesco - 2019 - repositorio.unesp.br
FGFR2 (Fibroblast Growth Factor Receptor 2) é uma proteína receptora que apresenta um
papel crucial na regulação do metabolismo celular, expressão gênica, crescimento, divisão …
papel crucial na regulação do metabolismo celular, expressão gênica, crescimento, divisão …
[图书][B] Oncogenic Fusion Protein FGFR2-PPHLN1 Functions through Ligand-independent Constitutive Kinase Activation, Membrane Trafficking and Membrane …
F Li - 2019 - search.proquest.com
Chromosomal translocations have been a focus in human cancer research. Since the
exponential advancement in sequencing technology, a number of actionable fusion proteins …
exponential advancement in sequencing technology, a number of actionable fusion proteins …
Fibroblast Growth Factor Receptor Inhibitors: Enhancing Therapeutic Strategies for Solid Tumors
C Hierro, J Tabernero - Targeting Cell Survival Pathways to Enhance …, 2019 - Elsevier
Despite advances in the last decades, cancer continues to be one of the main causes of
morbi-mortality worldwide. In fact, cancer remains the second leading cause of death …
morbi-mortality worldwide. In fact, cancer remains the second leading cause of death …
Drug resistance mechanisms of FGFR-driven cancers
Y Tanner - 2019 - qmro.qmul.ac.uk
The fibroblast growth factor (FGF) signalling pathway contributes to the regulation of a
variety of cellular functions, affecting differentiation, migration, proliferation, and survival …
variety of cellular functions, affecting differentiation, migration, proliferation, and survival …
[引用][C] Structure and Energy-based Analyses of FGFR2 Kinase Mutations Revealing Differences in Cancer and Syndrome Mutations and Inconclusive Nature of …
SV Sambare - 2019