Antimicrobial peptides (AMPs), critical components of the innate immune system, are widely
distributed throughout the animal and plant kingdoms. They can protect against a broad …

Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

Antimicrobial peptides (AMPs) occur in all kingdoms of life and are integral to host defense.
They have diverse structures and target a variety of organisms, both by nonspecific …

Antimicrobial peptides of multicellular organisms were first characterized in the 1980s by
investigators who felt that known systems of immunity could not explain what they observed …

Resistance to antibiotics is one of the main current threats to human health and every year
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …

Natural product antibiotics usually target the major biosynthetic pathways of bacterial cells
and the search for new targets outside these pathways has proven very difficult. Cell wall …

Plant defensins are antimicrobial host defense peptides expressed in all higher plants.
Performing a significant role in plant innate immunity, plant defensins display potent activity …

There is an urgent need to discover new active drugs to combat methicillin-resistant
Staphylococcus aureus, which is a serious threat to humans and animals and incompletely …

Infections caused by drug-resistant “superbugs” pose an urgent public health threat due to
the lack of effective drugs; however, certain mammalian proteins with intrinsic antibacterial …

Resistance against commonly used antibiotics has emerged in all bacterial pathogens. In
fact, there is no antibiotic currently in clinical use against which resistance has not been …