[HTML][HTML] Therapeutic novelties in migraine: new drugs, new hope?

TP Do, S Guo, M Ashina - The journal of headache and pain, 2019 - Springer
Background In the past decade, migraine research has identified novel drug targets. In this
review, we discuss recent data on emerging anti-migraine therapies. Main body The …

Pituitary adenylate cyclase-activating peptide (PACAP) signaling and the dark side of addiction

OW Miles, V May, SE Hammack - Journal of Molecular Neuroscience, 2019 - Springer
While addiction to drugs of abuse represents a significant health problem worldwide, the
behavioral and neural mechanisms that underlie addiction and relapse are largely unclear …

Pep‐lipid cubosomes and vesicles compartmentalized by Micelles from self‐assembly of multiple neuroprotective building blocks including a large peptide hormone …

A Angelova, M Drechsler, VM Garamus… - …, 2019 - Wiley Online Library
Structural control over design and formation of self‐assembled nanomaterials for
neuroprotection and neuroregeneration is crucial for their application in nanomedicine. Here …

Emerging treatment targets for migraine and other headaches

Z Bertels, AAA Pradhan - Headache: The Journal of Head and …, 2019 - Wiley Online Library
Migraine is a complex disorder that is characterized by an assortment of neurological and
systemic effects. While headache is the most prominent feature of migraine, a host of …

Molecular mechanisms involved in the protective effect of pituitary adenylate cyclase‐activating polypeptide in an in vitro model of amyotrophic lateral sclerosis

G Maugeri, AG D'Amico, DM Rasà… - Journal of Cellular …, 2019 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the loss of upper and lower motor neurons. Based on transcriptional profiles of motor cortex …

Mechanisms underlying a critical period of respiratory development in the rat

MTT Wong-Riley, Q Liu, X Gao - Respiratory physiology & neurobiology, 2019 - Elsevier
Twenty-five years ago, Filiano and Kinney (1994) proposed that a critical period of postnatal
development constitutes one of the three risk factors for sudden infant death syndrome …

Immunohistochemical analysis of the mouse celiac ganglion: An integrative relay station of the peripheral nervous system

CL Kaestner, EH Smith, SG Peirce… - Journal of …, 2019 - Wiley Online Library
Celiac ganglia are important sites of signal integration and transduction. Their complex
neurochemical anatomy has been studied extensively in guinea pigs but not in mice. The …

[HTML][HTML] Pituitary adenylate cyclase-activating peptide (PACAP)-glutamate co-transmission drives circadian phase-advancing responses to intrinsically photosensitive …

PT Lindberg, JW Mitchell, PW Burgoon… - Frontiers in …, 2019 - frontiersin.org
Results from a variety of sources indicate a role for pituitary adenylate cyclase-activating
polypeptide (PACAP) in light/glutamate-induced phase resetting of the circadian clock …

[HTML][HTML] The PACAP-derived peptide MPAPO facilitates corneal wound healing by promoting corneal epithelial cell proliferation and trigeminal ganglion cell axon …

Z Wang, W Shan, H Li, J Feng, S Lu, B Ou… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
It is well known that the cornea plays an important role in providing protection to the eye, but
it is fragile and vulnerable. To clarify the biological effects and molecular mechanisms of the …

Pituitary adenylate cyclase-activating polypeptide (PACAP) acts in the nucleus accumbens to reduce hedonic drive

MM Hurley, MR Robble, G Callan, SJ Choi… - International Journal of …, 2019 - nature.com
Obesity develops, in part, due to frequent overconsumption. Therefore, it is important to
identify the regulatory mechanisms that promote eating beyond satiety. Previously, we have …