Diabetogenic action of statins: mechanisms

R Carmena, DJ Betteridge - Current atherosclerosis reports, 2019 - Springer
Abstract Purpose of Review Observational studies and meta-analyses of randomized clinical
trials data have revealed a 10–12% increased risk of new-onset diabetes (NOD) associated …

Mechanisms of statin‐induced new‐onset diabetes

M Paseban, AE Butler… - Journal of cellular …, 2019 - Wiley Online Library
Statins, with their lipid‐lowering properties, are a first‐line therapy for the prevention of
cardiovascular diseases. Recent evidence, however, suggests that statins can increase the …

Statin use and reduced risk of biliary tract cancers in the UK Clinical Practice Research Datalink

Z Liu, R Alsaggaf, KA McGlynn, LA Anderson, HT Tsai… - Gut, 2019 - gut.bmj.com
Objective To evaluate the association between statin use and risk of biliary tract cancers
(BTC). Design This is a nested case–control study conducted in the UK Clinical Practice …

Metabolic effects of cardiovascular drugs

G Fragasso, A Margonato, R Spoladore… - Trends in …, 2019 - Elsevier
Prescription of cardiovascular drugs is aimed at preventing and treating morbid conditions
affecting the cardiovascular system. However, apart from their primary therapeutic target …

[HTML][HTML] Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells

L Zhu, G Wu, X Yang, X Jia, J Li, X Bai, W Li, Y Zhao… - Scientific Reports, 2019 - nature.com
Elevated plasma low density lipoprotein (LDL) is an established risk factor for cardiovascular
disease. In addition to being able to cross the endothelial barrier to become accumulated in …

Definition, diagnostic criteria, screening, diagnosis, and classification of diabetes and categories of glucose intolerance

LP Nandhini, S Kamalanathan, J Sahoo - The Diabetes Textbook: Clinical …, 2019 - Springer
The diagnostic criteria for diabetes mellitus (DM) have undergone a sea change over the
last several decades. The specific cutoff points for diagnosing DM still remain a matter of …

[HTML][HTML] Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice

E Lorza-Gil, M Garcia-Arevalo, BC Favero… - Journal of translational …, 2019 - Springer
Background HMG-CoA reductase inhibitors (statins) are cholesterol-lowering drugs widely
used to treat hypercholesterolemia and prevent cardiovascular disease. Statins are …

Statins and the risk of diabetes: an evidence-based review

MV Leonova - Pharmateca, 2019 - gynecology.orscience.ru
The present article reviews evidence about the effect of statins on the risk of developing
diabetes mellitus (DM). A literature search was performed using databases of biomedical …

Estatinas e Diabetes:" friends or foes"

LSG Rodrigues - 2019 - estudogeral.uc.pt
No âmbito da unidade curricular Estágio Curricular do Mestrado Integrado em
CiênciasFarmacêuticas da Faculdade de Farmácia da Universidade de Coimbra, o …

Статины и риск развития сахарного диабета: данные доказательной медицины

МВ Леонова - Фарматека, 2019 - elibrary.ru
Представлен научный обзор данных о влиянии статинов на риск развития сахарного
диабета (СД), согласно доказательствам разного уровня. Проведен поиск зарубежных …