Experience plays an essential role in building brain architecture after birth. The question we
address in this paper is what happens to brain and behavior when a young child is deprived …

This review integrates scientific knowledge obtained over the past few decades on the
biological mechanisms that contribute to the profound association between exposure to …

Background Recent conceptual models argue that early life adversity (ELA) accelerates
development, which may contribute to poor mental and physical health outcomes. Evidence …

There is clear evidence that early deprivation in the form of early institutional care affects
children both immediately and long after they are removed from the institution. This article …

The objective of the present study is to synthesize the existing empirical literature and
perform a meta-analysis of published data on the relationship between cortisol and telomere …

Objective Childhood maltreatment is a major risk factor for the development of behavioral
problems and poor physical and mental health. Accelerated cellular aging, through reduced …

Background Given the ethical limitations of exposing children to experimentally manipulated
adverse experiences, evidence of the effects of parent-child separation on subsequent …

Objective To test alterations in placental cellular aging as one pathway by which maternal
early adversity influences physiologic development in her offspring. Methods Maternal report …

Cancer remains one of the leading causes of death worldwide, especially lung cancer.
Chemotherapeutic drugs are commonly used for lung cancer treatment; nonetheless …

We apply a biopsychosocial approach to introduce early‐in‐life experiences that explain a
significant part of the male preponderance in the perpetration of violence. Early caregiver …