[HTML][HTML] Recent therapeutic trends and promising targets in triple negative breast cancer
SY Hwang, S Park, Y Kwon - Pharmacology & therapeutics, 2019 - Elsevier
Breast cancer accounts for 25% of all types of cancer in women, and triple negative breast
cancer (TNBC) comprises around 15~ 20% of breast cancers. Conventional chemotherapy …
cancer (TNBC) comprises around 15~ 20% of breast cancers. Conventional chemotherapy …
Disparity of race reporting and representation in clinical trials leading to cancer drug approvals from 2008 to 2018
Importance Representative racial/ethnic participation in research, especially in clinical trials
that establish standards of care, is necessary to minimize disparities in outcomes and to …
that establish standards of care, is necessary to minimize disparities in outcomes and to …
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines
Recent work points to a lack of diversity in genomics studies from genome-wide association
studies to somatic (tumor) genome analyses. Yet, population-specific genetic variation has …
studies to somatic (tumor) genome analyses. Yet, population-specific genetic variation has …
Immune microenvironment of triple-negative breast cancer in African-American and Caucasian women
T O'Meara, A Safonov, D Casadevall, T Qing… - Breast cancer research …, 2019 - Springer
Abstract Purpose African-American (AA) patients with triple-negative breast cancer (TNBC)
are less likely to achieve pathologic complete response from neoadjuvant chemotherapy …
are less likely to achieve pathologic complete response from neoadjuvant chemotherapy …
Atypical Chemokine Receptor 1 (DARC/ACKR1) in Breast Tumors Is Associated with Survival, Circulating Chemokines, Tumor-Infiltrating Immune Cells, and African …
Background: Tumor-specific immune response is an important aspect of disease prognosis
and ultimately impacts treatment decisions for innovative immunotherapies. The atypical …
and ultimately impacts treatment decisions for innovative immunotherapies. The atypical …
Dancing from bottoms up–roles of the POZ-ZF transcription factor Kaiso in cancer
The POZ-ZF transcription factor Kaiso was discovered two decades ago as a binding partner
for p120 ctn. Since its discovery, roles for Kaiso in diverse biological processes (epithelial-to …
for p120 ctn. Since its discovery, roles for Kaiso in diverse biological processes (epithelial-to …
Disparities in breast cancer diagnosis for immigrant women in Ontario and BC: results from the CanIMPACT study
AK Lofters, ML McBride, D Li, M Whitehead… - BMC cancer, 2019 - Springer
Abstract Background In Canada, clinical practice guidelines recommend breast cancer
screening, but there are gaps in adherence to recommendations for screening, particularly …
screening, but there are gaps in adherence to recommendations for screening, particularly …
[HTML][HTML] Reporting of race in genome and exome sequencing studies of cancer: a scoping review of the literature
A Nugent, KR Conatser, LL Turner, JT Nugent… - Genetics in …, 2019 - Elsevier
Purpose Minorities are often underrepresented in clinical cancer research yet the frequency
of reporting of race in genomic sequencing studies of cancer is unknown. This scoping …
of reporting of race in genomic sequencing studies of cancer is unknown. This scoping …
The impact of molecular status on survival outcomes for invasive micropapillary carcinoma of the breast
Invasive micropapillary carcinoma (IMPC) is an uncommon variant of breast cancer.
Previous studies demonstrated this subtype is often hormone receptor (HR)‐positive …
Previous studies demonstrated this subtype is often hormone receptor (HR)‐positive …
[HTML][HTML] Genomic analysis of racial differences in triple negative breast cancer
CS Chang, E Kitamura, J Johnson, R Bollag… - Genomics, 2019 - Elsevier
Triple negative breast cancer (TNBC) is more prevalent in African Americans (AAs), has a
more aggressive clinical course including a higher mortality rate and an increased …
more aggressive clinical course including a higher mortality rate and an increased …