Maternal obesity in pregnancy is associated with neurobehavioral problems in the offspring.
Establishing causality has been challenging in existing human studies, due to confounding …

Consumption of a high-fat diet has long been known to increase risk for obesity, diabetes,
and the metabolic syndrome. Further evidence strongly suggests that these same metabolic …

Overweight and obesity are a worldwide pandemic affecting billions of people. These
conditions have been associated with a chronic low-grade inflammatory state that is …

Maternal environmental factors such as diet have profound effects on offspring development
and later health. The hypothalamic-pituitary-adrenal (HPA) axis is an important stress …

Diet is increasingly being recognised as an important contributor to mental health. A diet
high in sugar and polyunsaturated fatty acids can have negative consequences for disease …

This study aimed at investigating the metabolic and behavioural effects of troxerutin
treatment in the offspring of high fat diet (HFD) fed dams. Female Wistar rats (n= 40) …

Objective: The main goal of the present study was to investigate the effects of two maternal
high-fat diets with different energy densities on the somatic growth, reflex ontogeny, and …

Stem/progenitor cells are maintained by a chromatin environment, mediated in part by
Polycomb group (PcG) proteins, which depress differentiation. The trophoblast-specific PcG …

Acute elevations in endogenous CORT caused by stress or exogenous administration
potentiate inflammatory gene expression. Maternal obesity through high-fat diets (HFD) has …