BACKGROUND A defining feature of sexual reproduction is the transmission of genomic
information from both parents to the offspring. There is now compelling evidence that the …

Mammalian sperm RNA is increasingly recognized as an additional source of paternal
hereditary information beyond DNA. Environmental inputs, including an unhealthy diet …

The most fundamental process for the perpetuation of a species is the transfer of information
from parent to offspring. Although genomic DNA contributes to the majority of the …

Genetic studies traditionally focus on DNA as the molecule that passes information on from
parents to their offspring. Changes in the DNA code alter heritable information and can more …

Gametogenesis, the process of forming mature germ cells, is an integral part of both an
individual's and a species' health and well-being. This chapter focuses on critical male and …

The profound influence of environmental chemicals on human health including inducing life-
threatening gene mutation has been publicly recognized. Being a substitute for the …

Bisphenol A (BPA) is an endocrine disruptor whose ubiquitous presence in the environment
has been related with impairment of male reproduction. BPA can cause both transcriptomic …

Motivation Quantitative detection of histone modifications has emerged in the recent years
as a major means for understanding such biological processes as chromosome packaging …

Modifications to DNA and histone proteins serve a critical regulatory role in the developing
and adult brain, and over a decade of research has established the importance of these …

Epigenetics refers to the heritable changes in gene expression without a change in the DNA
sequence itself. Two of these major changes include aberrant DNA methylation as well as …