Parkinson's disease (PD) is a neurodegenerative disease characterized by a progressive
loss of dopaminergic neurons from the nigrostriatal pathway, formation of Lewy bodies, and …

Research into the immunological processes implicated in cancer has yielded a basis for the
range of immunotherapies that are now considered the fourth pillar of cancer treatment …

Glioblastoma multiforme (GBM) is an aggressive primary brain tumor, for which there is no
cure. Treatment effectiveness for GBM has been limited due to tumor heterogeneity, an …

Foam cell formation and further accumulation in the subendothelial space of the vascular
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …

The tumor stromal microenvironments (TSM) including stromal cells and extracellular matrix
(ECM) form an abominable barrier hampering nanoparticles accessibility to cancer cells …

Efficient delivery of therapeutic RNA beyond the liver is the fundamental obstacle preventing
its clinical utility. Lipid conjugation increases plasma half-life and enhances tissue …

Immunostimulatory agents, including adjuvants, cytokines, and monoclonal antibodies, hold
great potential for the treatment of cancer. However, their direct administration often results …

Pancreatic cancer is a highly aggressive malignancy that strongly resists extant treatments.
The failure of existing therapies is majorly attributed to the tough tumor microenvironment …

Atherosclerosis is the root of approximately one‐third of global mortalities. Nanotechnology
exhibits splendid prospects to combat atherosclerosis at the molecular level by engineering …

Drug delivery to the brain remains challenging mainly due to the blood-brain barrier (BBB)
that regulates the entrance of substances to the brain. Advances in nanotechnology have …