Type III secretion systems (T3SS) are widely distributed in Gram-negative microorganisms
and critical for host-pathogen and host-symbiont interactions with plants and animals …

Antibiotic resistance is an ever-increasing global problem. Major commercial antibiotics
often fail to fight common bacteria, and some pathogens have become multi-resistant …

Despite being fundamentally important and having direct therapeutic implications, the
functional genomics of the clinical isolates of multidrug-resistant (MDR) pathogens is often …

Different works have explored independently the evolution toward antibiotic resistance and
the role of eco-adaptive mutations in the adaptation to a new habitat (as the infected host) of …

The study of the acquisition of antibiotic resistance (AR) has mainly focused on inherited
processes, namely, mutations and acquisition of AR genes. However, inducible …

Acinetobacter is an important opportunistic, multidrug resistant pathogen causing majority of
nosocomial infections worldwide. The multidrug resistance is attributed by a plethora of …

铜绿假单胞菌是临床上重要的条件致病菌, 具有多种毒力因子且极易产生耐药性. Ⅲ
型分泌系统(Type Ⅲ secretion system, T3SS) 是铜绿假单胞菌中重要的毒性因子分泌系统 …

Antibiotics have been widely used for treating bacterial infectious diseases. However, the
rapidly emerging of antibiotic resistance has dramatically decreased the efficacy of …

The emergence of multidrug-resistance pathogens has called for alternative therapies to
treat bacterial infections. Pseudomonas aeruginosa is an opportunistic pathogen that often …