Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

Nutrient sensing is critical for adaptation of fungi to environmental and host conditions. The
conserved cAMP/PKA signaling pathway contributes to adaptation by sensing the …

More than 1.5 million fungal species are estimated to live in vastly different environmental
niches. Despite each unique host environment, fungal cells sense certain fundamentally …

Environmental fungi are globally ubiquitous and human exposure is near universal.
However, relatively few fungal species are capable of infecting humans, and among fungi …

Cryptococcus species utilize a variety of sexual reproduction mechanisms, which generate
genetic diversity, purge deleterious mutations, and contribute to their ability to occupy myriad …

Living organisms are constantly exposed to DNA damage stress caused by endogenous
and exogenous events. Eukaryotic cells have evolutionarily conserved DNA damage …

Cryptococcus neoformans is a human pathogenic yeast that causes hundreds of thousands
of deaths worldwide among susceptible individuals, in particular, HIV+ patients. This yeast …

Abstract Purpose of Review The aim of this review is to give an overall idea of Cryptococcus
biology paying special attention to its capacity to adapt through its morphogenetic program …

Abstract Purpose of Review To review recent data on the role that B cells and/or antibody-
based immunity play in host defense against Cryptococcus neoformans (Cn). Recent …

The fungal pathogens encounter ever-changing conditions during their pathogenic life
cycles, including shifts from the environment to the human host. Fungi have evolved many …