Current and future perspectives of liquid biopsies in genomics-driven oncology
Precision oncology seeks to leverage molecular information about cancer to improve patient
outcomes. Tissue biopsy samples are widely used to characterize tumours but are limited by …
outcomes. Tissue biopsy samples are widely used to characterize tumours but are limited by …
Cancer biomarker discovery and translation: proteomics and beyond
VA Hristova, DW Chan - Expert review of proteomics, 2019 - Taylor & Francis
Introduction: Cancer is often diagnosed at late stages when the chance of cure is relatively
low and although research initiatives in oncology discover many potential cancer …
low and although research initiatives in oncology discover many potential cancer …
Metabolomics in the study of retinal health and disease
I Laíns, M Gantner, S Murinello, JA Lasky-Su… - Progress in retinal and …, 2019 - Elsevier
Metabolomics is the qualitative and quantitative assessment of the metabolites (small
molecules< 1.5 kDa) in body fluids. The metabolites are the downstream of the genetic …
molecules< 1.5 kDa) in body fluids. The metabolites are the downstream of the genetic …
Discovery and validation of clinical biomarkers of cancer: a review combining metabolomics and proteomics
A Srivastava, DJ Creek - Proteomics, 2019 - Wiley Online Library
Early detection and diagnosis of cancer can allow timely medical intervention, which greatly
improves chances of survival and enhances quality of life. Biomarkers play an important role …
improves chances of survival and enhances quality of life. Biomarkers play an important role …
[HTML][HTML] A review on MS-based blood biomarkers for Alzheimer's disease
P Oeckl, M Otto - Neurology and Therapy, 2019 - Springer
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia and
there is no cure to date. Biomarkers in cerebrospinal fluid (CSF) are already included in the …
there is no cure to date. Biomarkers in cerebrospinal fluid (CSF) are already included in the …
Mass spectrometry: A platform for biomarker discovery and validation for Alzheimer's and Parkinson's diseases
EM Cilento, L Jin, T Stewart, M Shi… - Journal of …, 2019 - Wiley Online Library
Accurate, reliable, and objective biomarkers for Alzheimer's disease (AD), Parkinson's
disease (PD), and related age‐associated neurodegenerative disorders are urgently …
disease (PD), and related age‐associated neurodegenerative disorders are urgently …
[HTML][HTML] Exploring serum and immunoglobulin G N-glycome as diagnostic biomarkers for early detection of breast cancer in Ethiopian women
AG Gebrehiwot, DS Melka, YM Kassaye, T Gemechu… - BMC cancer, 2019 - Springer
Background Alterations in protein glycosylation patterns have potentially been targeted for
biomarker discovery in a wide range of diseases including cancer. Although there have …
biomarker discovery in a wide range of diseases including cancer. Although there have …
[HTML][HTML] The relevance of mass spectrometry analysis for personalized medicine through its successful application in cancer “Omics”
CA Ciocan-Cartita, A Jurj, M Buse, D Gulei… - International Journal of …, 2019 - mdpi.com
Mass spectrometry (MS) is an essential analytical technology on which the emerging omics
domains; such as genomics; transcriptomics; proteomics and metabolomics; are based. This …
domains; such as genomics; transcriptomics; proteomics and metabolomics; are based. This …
[HTML][HTML] Development of parallel reaction monitoring assays for cerebrospinal fluid proteins associated with Alzheimer's disease
A Andersson, J Remnestål, B Nellgård, H Vunk… - Clinica Chimica …, 2019 - Elsevier
Detailed knowledge of protein changes in cerebrospinal fluid (CSF) across healthy and
diseased individuals would provide a better understanding of the onset and progression of …
diseased individuals would provide a better understanding of the onset and progression of …
Ovarian cancer classification using serum proteomic profiling and wavelet features a comparison of machine learning and features selection algorithms
AM Alqudah - Journal of Clinical Engineering, 2019 - journals.lww.com
Ovarian cancer is one the common cancers that in women such pathological disease within
an organ might lead to noticeable changes in the proteomic patterns in serum. Mass …
an organ might lead to noticeable changes in the proteomic patterns in serum. Mass …