Abstract Development of central nervous system (CNS) is regulated by both intrinsic and
peripheral signals. Previous studies have suggested that environmental factors affect …

Depression and obesity are common conditions with major public health implications that
tend to co-occur within individuals. The relationship between these conditions is …

Major depressive disorder (MDD) is one of the most disabling psychiatric disorders.
Approximately one‐third of the patients with MDD are treatment resistant to the current …

Akkermansia muciniphila, a symbiotic bacterium of the mucus layer, can utilize mucin as its
sole carbon, nitrogen, and energy source. As an abundant resident in the intestinal tract of …

Background Inflammasomes have been found to interact with the gut microbiota, and this
effect is associated with depression, but the mechanisms underlying this interaction have not …

Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

Patients with chronic neuropathic pain frequently suffer from symptoms of anhedonia, which
is a core symptom of depression. Accumulating studies suggest that gut microbiota may play …

Major depressive disorder is the main cause of disability worldwide with imperfect treatment
options. However, novel therapeutic approaches are currently discussed, from augmentation …

Pathological substance use disorders represent a major public health crisis with limited
effective treatment options. While much work has been done to understand the neuronal …

Socioeconomic inequalities in health and mortality are well established, but the biological
mechanisms underlying these associations are less understood. In parallel, the gut …