Ultraviolet radiation (UVR) has numerous effects on skin, including DNA damage, tanning,
vitamin D synthesis, carcinogenesis, and immunomodulation. Keratinocytes containing …

Cutaneous melanoma represents the most aggressive form of skin cancer, whereas vitiligo
is an autoimmune disorder that leads to progressive destruction of skin melanocytes …

Mitochondrial dysregulation has been implicated in oxidative stress-induced melanocyte
destruction in vitiligo. However, the molecular mechanism underlying this process is merely …

In recent years, increased attention has been paid to the relationship between microbiota
and various diseases, especially immune-mediated diseases. Because conventional …

Background Peripheral blood skin-homing/cutaneous lymphocyte antigen (CLA)+ T cells
emerge as biomarkers of cutaneous immune activation in patients with inflammatory skin …

Autoimmune dermatoses targeting melanocytes have gained attention in human medicine
due to their progressive nature and the social impact suffered by affected individuals. In …

Oxidative stress is known to induce melanocyte death, but the underlying mechanisms are
incompletely understood. To identify oxidative stress‐induced global gene expression …

Background Vitiligo is an acquired autoimmune skin disorder. The often-visible lesions of
vitiligo have a major impact on patients' quality of life and the results of the treatment …

Background 8-methoxypsoralen (8-MOP) is one of the most commonly utilized drugs in
psoralen-ultraviolet A therapy for treatment of vitiligo. However, poor skin retention and …

Background: Narrow-band ultraviolet B (NB-UVB) phototherapy is a mainstay treatment in
vitiligo. However, data relative to repigmentation outcome, prognostic factors, and duration …