Sleep disturbances in patients with amyotrophic lateral sclerosis: current perspectives

M Boentert - Nature and science of sleep, 2019 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease inevitably leading
to generalized muscle weakness and premature death. Sleep disturbances are extremely …

[HTML][HTML] Diaphragmatic neurophysiology and respiratory markers in ALS

M De Carvalho, M Swash, S Pinto - Frontiers in neurology, 2019 - frontiersin.org
The main reason for short survival in amyotrophic lateral sclerosis (ALS) is involvement of
respiratory muscles. Severe compromise of diaphragmatic function due to marked loss of …

Respiratory involvement in patients with neuromuscular diseases: a narrative review

A Voulgaris, M Antoniadou, M Agrafiotis… - Pulmonary …, 2019 - Wiley Online Library
Respiratory muscle weakness is a major cause of morbidity and mortality in patients with
neuromuscular diseases (NMDs). Respiratory involvement in NMDs can manifest broadly …

Home mechanical ventilation for patients with amyotrophic lateral sclerosis: a Canadian Thoracic Society clinical practice guideline

KP Rimmer, M Kaminska, M Nonoyama, E Giannouli… - 2019 - Taylor & Francis
Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder involving both
upper and lower motor neurons that results in progressive weakness of skeletal muscles …

[HTML][HTML] Sleep, aging, and cellular health: Aged-related changes in sleep and protein homeostasis converge in neurodegenerative diseases

JM Hafycz, NN Naidoo - Frontiers in aging neuroscience, 2019 - frontiersin.org
Many neurodegenerative diseases manifest in an overall aged population, the pathology of
which is hallmarked by abnormal protein aggregation. It is known that across aging, sleep …

Sleep disordered breathing in Duchenne muscular dystrophy

H Sawnani - Paediatric respiratory reviews, 2019 - Elsevier
Symptoms of sleep disordered breathing (SDB) in younger boys with DMD are often poorly
perceived and/or articulated by the patients or their families. As a result it is the watchful eye …

Mechanisms of compensatory plasticity for respiratory motor neuron death

YB Seven, GS Mitchell - Respiratory physiology & neurobiology, 2019 - Elsevier
Respiratory motor neuron death arises from multiple neurodegenerative and traumatic
neuromuscular disorders. Despite motor neuron death, compensatory mechanisms …

Value of periodic transcutaneous daytime Carbon dioxide monitoring in screening for Respiratory failure in patients with Amyotrophic lateral sclerosis

MK Rafiq - Pakistan Journal of Neurological Sciences (PJNS), 2019 - ecommons.aku.edu
There is no single test currently available, which can predict respiratory failure in patients
with amyotrophic lateral sclerosis (ALS) with high sensitivity and specificity. This study …

Sleep Disturbances in Patients with Disorders of the Nerve and Muscle Diseases

JL Morales-Estrella, LS Aboussouan - Current Sleep Medicine Reports, 2019 - Springer
Abstract Purpose of Review Recognize sleep disorders associated with neuromuscular
diseases. Recent Findings Neuromuscular diseases can be associated with various sleep …

A Case-Based Approach to the Identification and Treatment of Sleep Disorders in Neurology Practice

JRP Zuzuárregui, EH During - Current Sleep Medicine Reports, 2019 - Springer
Abstract Purpose of Review We present a case-based approach to common sleep disorders
encountered in the clinic. Recent Findings Sleep disorders are common in neurologic …