Xist RNA in action: Past, present, and future

A Loda, E Heard - PLoS genetics, 2019 - journals.plos.org
In mammals, dosage compensation of sex chromosomal genes between females (XX) and
males (XY) is achieved through X-chromosome inactivation (XCI). The X-linked X-inactive …

Coding or noncoding, the converging concepts of RNAs

J Li, C Liu - Frontiers in genetics, 2019 - frontiersin.org
Technological advances over the past decade have unraveled the remarkable complexity of
RNA. The identification of small peptides encoded by long non-coding RNAs (lncRNAs) as …

Update of the FANTOM web resource: expansion to provide additional transcriptome atlases

M Lizio, I Abugessaisa, S Noguchi, A Kondo… - Nucleic acids …, 2019 - academic.oup.com
The FANTOM web resource (http://fantom. gsc. riken. jp/) was developed to provide easy
access to the data produced by the FANTOM project. It contains the most complete and …

RNA structure drives interaction with proteins

N Sanchez de Groot, A Armaos… - Nature …, 2019 - nature.com
The combination of high-throughput sequencing and in vivo crosslinking approaches leads
to the progressive uncovering of the complex interdependence between cellular …

LncRNAs in vascular biology and disease

V Simion, S Haemmig, MW Feinberg - Vascular pharmacology, 2019 - Elsevier
Accumulating studies indicate that long non-coding RNAs (lncRNAs) play important roles in
the regulation of diverse biological processes involved in homeostatic control of the vessel …

Computational models for lncRNA function prediction and functional similarity calculation

X Chen, YZ Sun, NN Guan, J Qu… - Briefings in …, 2019 - academic.oup.com
From transcriptional noise to dark matter of biology, the rapidly changing view of long non-
coding RNA (lncRNA) leads to deep understanding of human complex diseases induced by …

Long non-coding RNAs and the innate immune response

MR Hadjicharalambous, MA Lindsay - Non-coding RNA, 2019 - mdpi.com
Innate immunity provides the initial defence against infection and it is now clear that long
non-coding RNAs (lncRNAs) are important regulators of this response. Following activation …

Lnc SMAD5-AS1 as ceRNA inhibit proliferation of diffuse large B cell lymphoma via Wnt/β-catenin pathway by sponging miR-135b-5p to elevate expression of APC

CC Zhao, Y Jiao, YY Zhang, J Ning, YR Zhang… - Cell death & …, 2019 - nature.com
Diffuse large B cell lymphoma (DLBCL) is a common and fatal hematological malignancy.
Long noncoding RNAs (lncRNAs) have emerged as crucial biomarkers and regulators in …

[HTML][HTML] The function of miR-143, miR-145 and the MiR-143 host gene in cardiovascular development and disease

F Vacante, L Denby, JC Sluimer, AH Baker - Vascular Pharmacology, 2019 - Elsevier
Abstract Noncoding RNAs (long noncoding RNAs and small RNAs) are emerging as critical
modulators of phenotypic changes associated with physiological and pathological contexts …

Translation of small open reading frames: roles in regulation and evolutionary innovation

J Ruiz-Orera, MM Albà - Trends in Genetics, 2019 - cell.com
The translatome can be defined as the sum of the RNA sequences that are translated into
proteins in the cell by the ribosomal machinery. Until recently, it was generally assumed that …