Cells respond to both chemical and mechanical cues present within their microenvironment.
Various mechanical signals are detected by and transmitted to the cells through …

The mechanotransduction is the process by which cells sense mechanical stimuli such as
elasticity, viscosity, and nanotopography of extracellular matrix and translate them into …

The ability of mesenchymal stem cells to sense nanoscale variations in extracellular matrix
(ECM) compositions in their local microenvironment is crucial to their survival and their fate; …

Cells sense their environment by transducing mechanical stimuli into biochemical signals.
Commonly used tools to study cell mechanosensing provide limited spatial and force …

Cancer metastasis has been believed as a genetically programmed process that is
commonly marked by biochemical signals. Here using extracellular matrix control of cellular …

Biomimetically designed materials matching the chemical and mechanical properties of
tissue support higher mesenchymal stem cell (MSC) adhesion. However, directing cell …

Localized application of exogenous forces on soft biomaterials and cells is often essential
for the study of their response to external mechanical stimuli. Magnetic means of applying …

Angiogenesis inhibition is a promising approach to fight cancer. This strategy offers some
advantages in comparison with conventional drugs, such as the inhibition of single vessels …

For cellular adaptation in mechanical environments, it is important to consider transmission
of forces from the outside to the inside of cells via a focal molecular complex. The focal …

The knowledge of fundamental aspects in cell biology has rapidly increased in the last
decades also aided by the fabrication of artificial cell microenvironments in both 2-D and 3 …