Network-based prediction of drug combinations

F Cheng, IA Kovács, AL Barabási - Nature communications, 2019 - nature.com
Drug combinations, offering increased therapeutic efficacy and reduced toxicity, play an
important role in treating multiple complex diseases. Yet, our ability to identify and validate …

[PDF][PDF] Guía ESC/ESH 2018 sobre el diagnóstico y tratamiento de la hipertensión arterial

B Williams, G Mancia, W Spiering, E Agabiti Rosei… - Rev Esp …, 2019 - peroxfarma.com
La tarea de elaboración de GPC incluye la creación de herramientas educativas y
programas de implementación de las recomendaciones. Para su implementación, se …

2018 ESC/ESH Guidelines for the Management of Arterial Hypertension: The Task Force for the management of arterial hypertension of the European Society of …

B Williams, G Mancia, W Spiering… - … of Hypertension of …, 2019 - taylorfrancis.com
Guidelines summarize and evaluate available evidence with the aim of assisting health
professionals in selecting the best management strategies for an individual patient with a …

Nephrotic syndrome: oedema formation and its treatment with diuretics

S Gupta, RJ Pepper, N Ashman, SB Walsh - Frontiers in physiology, 2019 - frontiersin.org
Oedema is a defining element of the nephrotic syndrome. Its' management varies
considerably between clinicians, with no national or international clinical guidelines, and …

[HTML][HTML] Redefining diuretics use in hypertension: why select a thiazide-like diuretic?

M Burnier, G Bakris, B Williams - Journal of hypertension, 2019 - journals.lww.com
Diuretics are listed in hypertension guidelines as one of three equally weighted first-line
treatment options. In order to differentiate between antihypertensives, a lot of discussion has …

A review of the prescribing trend of thiazide‐type and thiazide‐like diuretics in hypertension: A UK perspective

RJ McNally, F Morselli, B Farukh… - British journal of …, 2019 - Wiley Online Library
Thiazide diuretics have been the cornerstone of hypertension treatment for> 5 decades.
Most recent European and American guidelines recommend both thiazide‐type and thiazide …

Drug-induced diabetes type 2: In silico study involving class B GPCRs

D Latek, E Rutkowska, S Niewieczerzal… - PloS one, 2019 - journals.plos.org
A disturbance of glucose homeostasis leading to type 2 diabetes mellitus (T2DM) is one of
the severe side effects that may occur during a prolonged use of many drugs currently …

[PDF][PDF] Uncontrolled arterial hypertension: kidney, neurohormonal imbalance, and approaches to antihypertensive drug therapy

OB Kuzmin, NN Buchneva, VV Zhezha, SV Serdyuk - Kardiologiia, 2019 - lib.ossn.ru
Resistant and refractory arterial hypertensions are two distinct clinical phenotypes of
uncontrolled arterial hypertension (AH), which differ in their sensitivity to antihypertensive …

Неконтролируемая артериальная гипертензия: почка, нейрогормональный дисбаланс и подходы к антигипертензивной лекарственной терапии

ОБ Кузьмин, НВ Бучнева, ВВ Жежа, СВ Сердюк - Кардиология, 2019 - lib.ossn.ru
Аннотация Резистентная и рефрактерная артериальная гипертензии (АГ)
представляют собой два разных клинических фенотипа неконтролируемой АГ …

Austrian consensus on high blood pressure 2019

T Weber, K Arbeiter, F Ardelt, J Auer, C Aufricht… - Wiener klinische …, 2019 - Springer
Erhöhter Blutdruck bleibt eine Hauptursache von kardiovaskulären Erkrankungen,
Behinderung und frühzeitiger Sterblichkeit in Österreich, wobei die Raten an Diagnose …