Cancer nanomedicine for combination cancer immunotherapy
Cancer immunotherapy is revolutionizing oncology. However, dose-limiting toxicities and
low patient response rates remain major challenges in the clinic. Cancer nanomedicine in …
low patient response rates remain major challenges in the clinic. Cancer nanomedicine in …
Three decades of messenger RNA vaccine development
R Verbeke, I Lentacker, SC De Smedt, H Dewitte - Nano Today, 2019 - Elsevier
In the early nineties, pioneering steps were taken in the use of mRNA as a therapeutic tool
for vaccination. In the following decades, an improved understanding of the mRNA …
for vaccination. In the following decades, an improved understanding of the mRNA …
Trial watch: dendritic cell vaccination for cancer immunotherapy
J Sprooten, J Ceusters, A Coosemans… - …, 2019 - Taylor & Francis
Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …
Emerging nano‐/microapproaches for cancer immunotherapy
Cancer immunotherapy has achieved remarkable clinical efficacy through recent advances
such as chimeric antigen receptor‐T cell (CAR‐T) therapy, immune checkpoint blockade …
such as chimeric antigen receptor‐T cell (CAR‐T) therapy, immune checkpoint blockade …
Co-delivery of cisplatin and doxorubicin by covalently conjugating with polyamidoamine dendrimer for enhanced synergistic cancer therapy
Because of the synergistic effects of drugs and minimal drug dose for cancer therapy,
combination chemotherapy is frequently used in the clinic. In this study, hyaluronic acid …
combination chemotherapy is frequently used in the clinic. In this study, hyaluronic acid …
Nanoparticle‐based nanomedicines to promote cancer immunotherapy: recent advances and future directions
Cancer immunotherapy is a promising cancer terminator by directing the patient's own
immune system in the fight against this challenging disorder. Despite the monumental …
immune system in the fight against this challenging disorder. Despite the monumental …
A concise review on cancer treatment methods and delivery systems
E Bidram, Y Esmaeili, H Ranji-Burachaloo… - Journal of Drug Delivery …, 2019 - Elsevier
The ultimate purpose of current cancer research is to develop a comprehensive treatment for
cancer. Recent studies have shown an increased interest in investigating the capacity of …
cancer. Recent studies have shown an increased interest in investigating the capacity of …
Broadening the message: a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells
R Verbeke, I Lentacker, K Breckpot, J Janssens… - ACS …, 2019 - ACS Publications
Messenger RNA encoding tumor antigens has the potential to evoke effective antitumor
immunity. This study reports on a nanoparticle platform, named mRNA Galsomes, that …
immunity. This study reports on a nanoparticle platform, named mRNA Galsomes, that …
The application of nanotechnology in enhancing immunotherapy for cancer treatment: current effects and perspective
Cancer immunotherapy is emerging as a promising treatment modality that suppresses and
eliminates tumors by re-activating and maintaining the tumor-immune cycle, and further …
eliminates tumors by re-activating and maintaining the tumor-immune cycle, and further …
[HTML][HTML] Nanosoldiers: A promising strategy to combat triple negative breast cancer
A Pawar, P Prabhu - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstracts The phenomenal rise in cancer over the past few years has made it the second
leading cause of death worldwide. Breast cancer constitutes the predominant cancer …
leading cause of death worldwide. Breast cancer constitutes the predominant cancer …