Revisiting the cholinergic hypothesis in Alzheimer's disease: emerging evidence from translational and clinical research
Scientific evidence collected over the past 4 decades suggests that a loss of cholinergic
innervation in the cerebral cortex of patients with Alzheimer's disease is an early pathogenic …
innervation in the cerebral cortex of patients with Alzheimer's disease is an early pathogenic …
Cholinesterase inhibitors for Alzheimer's disease: multitargeting strategy based on anti-Alzheimer's drugs repositioning
MT Kabir, MS Uddin, M Begum… - Current …, 2019 - ingentaconnect.com
In the brain, acetylcholine (ACh) is regarded as one of the major neurotransmitters. During
the advancement of Alzheimer's disease (AD) cholinergic deficits occur and this can lead to …
the advancement of Alzheimer's disease (AD) cholinergic deficits occur and this can lead to …
Discovery of δ-sultone-fused pyrazoles for treating Alzheimer's disease: Design, synthesis, biological evaluation and SAR studies
Y Xu, Z Zhang, X Jiang, X Chen, Z Wang… - European Journal of …, 2019 - Elsevier
A class of novel δ-sulfonolactone-fused pyrazole scaffold was prepared via sulfur (VI)
fluoride exchange (SuFEx) chemistry using aryl sulfonyl fluorides and pyrazolones. Enzyme …
fluoride exchange (SuFEx) chemistry using aryl sulfonyl fluorides and pyrazolones. Enzyme …
Neuroprotective effects of matrine on scopolamine-induced amnesia via inhibition of AChE/BuChE and oxidative stress
K Sun, Y Bai, R Zhao, Z Guo, X Su, P Li, P Yang - Metabolic Brain Disease, 2019 - Springer
The present study was designed to evaluate the effects of matrine (MAT) on scopolamine
(SCOP)-induced learning and memory impairment. After successive oral administration of …
(SCOP)-induced learning and memory impairment. After successive oral administration of …
[HTML][HTML] Correlation between donepezil and QTc prolongation and torsades de pointes: a very rare phenomenon
Dementia can be seen as a clinical syndrome featuring a decline in cognitive and
psychological abilities that can cause disability. Two major kinds of drugs are available: N …
psychological abilities that can cause disability. Two major kinds of drugs are available: N …
Biljni ekstrakti kao inhibitori kolinesteraza
P Jurić - 2019 - repozitorij.svkst.unist.hr
Cilj ovog rada je istražiti sposobnosti različitih ekstrakata i čistih spojeva koji dolaze kao
sastavnice ekstrakata u inhibiciji dvaju enzima važnih u patogenezi Alzheimerove bolesti; …
sastavnice ekstrakata u inhibiciji dvaju enzima važnih u patogenezi Alzheimerove bolesti; …
[引用][C] Yeni bir grup potansiyel anti-alzheimer etkili takrin-donepezil hibritleri üzerinde çalışmalar
G Bayraktar - Ege Üniversitesi Sağlık Bilimleri Enstitüsü, Doktora … - platform.almanhal.com
منصة المنهل لقد انتهت الجلسة. يرجى العمل على إعادة تحديث الصفحة إعادة تحديث يرجى الانتظار...
يتم تحضير الملف الاستخدام المجاني إذا كنت ترغب في الوصول الكامل إلى هذا المحتوى وقاعدة …
يتم تحضير الملف الاستخدام المجاني إذا كنت ترغب في الوصول الكامل إلى هذا المحتوى وقاعدة …
[引用][C] Farelerde skopolamin ile oluşturulan demans modelinde agomelatinin etkilerinin araştırılması
A Çelebi - platform.almanhal.com
منصة المنهل لقد انتهت الجلسة. يرجى العمل على إعادة تحديث الصفحة إعادة تحديث يرجى الانتظار...
يتم تحضير الملف الاستخدام المجاني إذا كنت ترغب في الوصول الكامل إلى هذا المحتوى وقاعدة …
يتم تحضير الملف الاستخدام المجاني إذا كنت ترغب في الوصول الكامل إلى هذا المحتوى وقاعدة …
[引用][C] Donepezil and rivastigmine: pharmacokinetic profile and brain-targeting after intramuscular application in rats
JZ Karasovaa, M Hrabinovaa, M Krejciovaa, D Juna…