Cancer nanotechnology: a new revolution for cancer diagnosis and therapy

VK Chaturvedi, A Singh, VK Singh… - Current drug …, 2019 - ingentaconnect.com
Background: Nanotechnology is gaining significant attention worldwide for cancer treatment.
Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …

Polymeric mixed micelles: improving the anticancer efficacy of single-copolymer micelles

AS Manjappa, PS Kumbhar, AB Patil… - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Mixed micelles self-assembled from two or more dissimilar block copolymers provide a
direct and convenient approach to improved drug delivery. The present review is focused on …

Polydopamine-tailored paclitaxel-loaded polymeric microspheres with adhered NIR-controllable gold nanoparticles for chemo-phototherapy of pancreatic cancer

A Banstola, TT Pham, JH Jeong, S Yook - Drug delivery, 2019 - Taylor & Francis
Chemotherapeutic drugs often used as a first-line treatment of pancreatic cancer (PC)
exhibit challenges due to resistance development, lack of selectivity, and tumor …

Co-delivery of paclitaxel and curcumin to foliate positive cancer cells using Pluronic-coated iron oxide nanoparticles

CG Hiremath, GB Heggnnavar… - Progress in …, 2019 - Springer
Active targeting of folic acid and passive targeting of magnetic nanoparticles to bring about
co-delivery of hydrophobic chemotherapeutic agents were the focus of this work. Co …

Folate receptor-mediated renal-targeting nanoplatform for the specific delivery of triptolide to treat renal ischemia/reperfusion injury

C Huang, T Zeng, J Li, L Tan, X Deng… - ACS Biomaterials …, 2019 - ACS Publications
Triptolide (TP) has been widely used in clinical medicine; however, it has created a dilemma
due to its toxicity and nonspecificity. Here, we reported a biocompatible and high-efficiency …

Molecular understanding of interactions, structure, and drug encapsulation efficiency of Pluronic micelles from dissipative particle dynamics simulations

G Kacar - Colloid and Polymer Science, 2019 - Springer
In this work, we employ coarse-grained dissipative particle dynamics simulations with the
hydrogen bonds added explicitly to study the drug encapsulation property, structure, and …

Dexamethasone loaded multi-layer poly-l-lactic acid/pluronic P123 composite electrospun nanofiber scaffolds for bone tissue engineering and drug delivery

G Birhanu, S Tanha, H Akbari Javar… - Pharmaceutical …, 2019 - Taylor & Francis
In tissue engineering, it is common to mix drugs that can control proliferation and
differentiation of cells into polymeric solutions as part of composite to get bioactive scaffolds …

Next-generation paclitaxel-nanoparticle formulation for pancreatic cancer treatment

AE Massey, M Sikander, N Chauhan, S Kumari… - … , Biology and Medicine, 2019 - Elsevier
Pancreatic cancer (PanCa) is a major cause of cancer-related death due to limited
therapeutic options. As pancreatic tumors are highly desmoplastic, they prevent appropriate …

Multifunctionalized micelles facilitate intracellular doxorubicin delivery for reversing multidrug resistance of breast cancer

A Cao, P Ma, T Yang, Y Lan, S Yu, L Liu… - Molecular …, 2019 - ACS Publications
Intracellular doxorubicin (DOX) pumping out of cells through the P-glycoprotein (P-gp)
transporter leads to the reduction of intracellular DOX levels and induces multidrug …

[HTML][HTML] Hypericin photodynamic activity in DPPC liposome. PART I: biomimetism of loading, location, interactions and thermodynamic properties

FAP de Morais, RS Gonçalves, BH Vilsinski… - … of Photochemistry and …, 2019 - Elsevier
Hypericin (Hyp) is a potential photosensitizer drug for Photodynamic Therapy (PDT).
However, the high lipophilicity of Hyp prevents its preparation in water. To overcome the Hyp …