American Society of Hematology 2019 guidelines for sickle cell disease: cardiopulmonary and kidney disease

RI Liem, S Lanzkron, T D. Coates, L DeCastro… - Blood …, 2019 - ashpublications.org
Background: Prevention and management of end-organ disease represent major
challenges facing providers of children and adults with sickle cell disease (SCD) …

End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings

AT Farrell, J Panepinto, AA Desai, AA Kassim… - Blood …, 2019 - ashpublications.org
To address the global burden of sickle cell disease and the need for novel therapies, the
American Society of Hematology partnered with the US Food and Drug Administration to …

Sickle cell disease nephropathy: an update on risk factors and potential biomarkers in pediatric patients

AR Belisario, AAS da Silva, CVM Silva… - Biomarkers in …, 2019 - Taylor & Francis
One of the major chronic complications of sickle cell disease (SCD) is sickle cell
nephropathy. The aim of this review is to discuss the pathophysiology, natural history …

Sickle cell disease in the era of precision medicine: looking to the future

MH Steinberg, S Kumar, GJ Murphy… - Expert review of …, 2019 - Taylor & Francis
Introduction: Sickle cell anemia is a Mendelian disease that is noted for the heterogeneity of
its clinical expression. Because of this, providing an accurate prognosis has been a longtime …