Transcription-driven chromatin repression of Intragenic transcription start sites

M Nielsen, R Ard, X Leng, M Ivanov, P Kindgren… - PLoS …, 2019 - journals.plos.org
Progression of RNA polymerase II (RNAPII) transcription relies on the appropriately
positioned activities of elongation factors. The resulting profile of factors and chromatin …

Transcriptome maps of general eukaryotic RNA degradation factors

S Sohrabi-Jahromi, KB Hofmann, A Boltendahl, C Roth… - Elife, 2019 - elifesciences.org
RNA degradation pathways enable RNA processing, the regulation of RNA levels, and the
surveillance of aberrant or poorly functional RNAs in cells. Here we provide transcriptome …

Transcription-dependent targeting of Hda1C to hyperactive genes mediates H4-specific deacetylation in yeast

SD Ha, S Ham, MY Kim, JH Kim, I Jang, BB Lee… - Nature …, 2019 - nature.com
In yeast, Hda1 histone deacetylase complex (Hda1C) preferentially deacetylates histones
H3 and H2B, and functionally interacts with Tup1 to repress transcription. However, previous …

Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs transcriptome

U Szachnowski, S Andjus, D Foretek… - Life Science …, 2019 - life-science-alliance.org
Antisense long noncoding (aslnc) RNAs are extensively degraded by the nuclear exosome
and the cytoplasmic exoribonuclease Xrn1 in the budding yeast Saccharomyces cerevisiae …

Cytoplasmic mRNA decay factors modulate RNA polymerase II processivity in 5'and 3'gene regions in yeast

J Fischer, YS Song, N Yosef, J di Iulio, LS Churchman… - bioRxiv, 2019 - biorxiv.org
Abstract mRNA levels are determined by the balance between mRNA synthesis and decay.
Factors that mediate both processes, including the 5'to 3'exonuclease Xrn1, are responsible …

[PDF][PDF] Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs

U Szachnowski, S Andus, D Foretek, A Morillon… - scholar.archive.org
1 Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs
transcriptome Ugo Szachnowski1, Sara Andus1 Page 1 1 Endogenous RNAi pathway …

[PDF][PDF] Gbp2 and Hrb1 continue their mRNA quality control in the cytoplasm and take part in Nonsense Mediated Decay

S Grosse - 2019 - core.ac.uk
The eukaryotic mRNA life cycle is orchestrated by many pathways. Every aspect of this life
cycle is associated with quality control factors. This tight coupling of mRNA transcription …

[PDF][PDF] Transcriptome maps of general eukaryotic RNA degradation factors and identification and functional characterization of the novel mRNA modification N3 …

KB Hofmann - 2019 - ediss.uni-goettingen.de
2. Hilfe Dritter wurde bis jetzt und wird auch künftig nur in wissenschaftlich vertretbarem und
prüfungsrechtlich zulässigem Ausmaß in Anspruch genommen. Insbesondere werden alle …

An essential RNA-binding lysine residue in the Nab3 RRM domain undergoes mono and trimethylation

KY Lee, A Chopra, K Biggar, MD Meneghini - bioRxiv, 2019 - biorxiv.org
Abstract The Nrd1-Nab3-Sen1 (NNS) complex integrates molecular inputs to direct
termination of noncoding transcription in budding yeast. NNS is positively regulated by …

Caractérisation du domaine C-terminal de l'ARN polymérase II et de la phosphatase Glc7 dans la terminaison transcriptionnelle chez Saccharomyces cerevisiae

P Collin - 2019 - papyrus.bib.umontreal.ca
La terminaison transcriptionnelle de l'ARN polymérase II (ARNPII) est l'étape de la
transcription la moins bien comprise. Deux modèles ont toutefois été proposés pour la …