Pharmacological effects of natural Ganoderma and its extracts on neurological diseases: A comprehensive review
C Zhao, C Zhang, Z Xing, Z Ahmad, JS Li… - International Journal of …, 2019 - Elsevier
Ganoderma, has been used for clinical applications for thousands of years as a highly-
nutritious and significantly-effective medicinal herb. The active components and efficacy of …
nutritious and significantly-effective medicinal herb. The active components and efficacy of …
[HTML][HTML] Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons
X Zhang, T Nagai, RU Ahammad, K Kuroda… - Neurochemistry …, 2019 - Elsevier
Medium spiny neurons (MSNs) expressing dopamine D1 receptor (D1R) or D2 receptor
(D2R) are major components of the striatum. Stimulation of D1R activates protein kinase A …
(D2R) are major components of the striatum. Stimulation of D1R activates protein kinase A …
Expression of the cerebral olfactory receptors Olfr110/111 and Olfr544 is altered during aging and in Alzheimer's disease-like mice
F Gaudel, D Stephan, V Landel, G Sicard, F Féron… - Molecular …, 2019 - Springer
A growing number of studies report the expression of olfactory receptors (ORs) in many non-
chemosensory tissues and organs. However, within the brain, very few ectopic ORs are …
chemosensory tissues and organs. However, within the brain, very few ectopic ORs are …
Differential enhancement of ERK, PKA and Ca2+ signaling in direct and indirect striatal neurons of Parkinsonian mice
LL Mariani, S Longueville, JA Girault, D Herve… - Neurobiology of …, 2019 - Elsevier
Parkinson's disease (PD) is characterized by severe locomotor deficits due to the
disappearance of dopamine (DA) from the dorsal striatum. The development of PD …
disappearance of dopamine (DA) from the dorsal striatum. The development of PD …
Gnal haploinsufficiency causes genomic instability and increased sensitivity to haloperidol
MM Khan, J Xiao, TJ Hollingsworth, D Patel… - Experimental …, 2019 - Elsevier
GNAL encodes guanine nucleotide-binding protein subunit Gα (olf) which plays a key role in
striatal medium spiny neuron (MSN)-dopamine signaling. GNAL loss-of-function mutations …
striatal medium spiny neuron (MSN)-dopamine signaling. GNAL loss-of-function mutations …
Purinergic pharmacology
F Ciruela, KA Jacobson - Frontiers in Pharmacology, 2019 - frontiersin.org
The purine nucleotides and nucleosides constitute important extracellular signaling
molecules acting as neurotransmitters and neuromodulators. Indeed, extracellular …
molecules acting as neurotransmitters and neuromodulators. Indeed, extracellular …