[HTML][HTML] A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune …
The Hippo pathway is an emerging signaling pathway that plays important roles in organ
size control, tissue homeostasis, tumorigenesis, metastasis, drug resistance, and immune …
size control, tissue homeostasis, tumorigenesis, metastasis, drug resistance, and immune …
[HTML][HTML] A tyrosine kinase expression signature predicts the post-operative clinical outcome in triple negative breast cancers
Triple negative breast cancer (TNBC) represent 15% of breast cancers. Histoclinical features
and marketed prognostic gene expression signatures (GES) failed to identify good-and poor …
and marketed prognostic gene expression signatures (GES) failed to identify good-and poor …
[HTML][HTML] Lack of expression of ALK and CD30 in breast carcinoma by immunohistochemistry irrespective of tumor characteristics
S Nassif, ZM El-Zaatari, M Attieh, M Hijazi… - Medicine, 2019 - journals.lww.com
CD30 is a member of the tumor necrosis factor family of cell surface receptors normally
expressed in lymphocytes, as well as some lymphomas, but has been described in other …
expressed in lymphocytes, as well as some lymphomas, but has been described in other …
[HTML][HTML] The Association Between Anaplastic Lymphoma Kinase (ALK) with Histological Grading and Molecular Subtypes in Invasive Breast Carcinoma
RF Doloksaribu, TI Alferraly - … Kinase (ALK) with Histological Grading and …, 2019 - ijrp.org
Background: Breast carcinoma is the second most common cancer in the world and is the
most common cancer among women. Research on protein expression is associated with …
most common cancer among women. Research on protein expression is associated with …
Molecular simulation studies on the binding activity and selectivity of 3-amino-phenyl-5-chloro-pyrimidine-2, 4-diamine derivatives in complexes with kinases c-Met …
YL Pan, YL Liu, JZ Chen - Molecular Simulation, 2019 - Taylor & Francis
Receptor tyrosine kinases c-Met and ALK have been demonstrated to be important
therapeutic targets for cancer therapy. However, selectivity and drug resistance could hinder …
therapeutic targets for cancer therapy. However, selectivity and drug resistance could hinder …