Colorectal cancer (CRC), as a prominent cause of cancer-related deaths, has historically
been notable worldwide and many attempts have been made to raise the overall survival of …

Background: Studies evaluating the prognostic significance of programmed death-ligand 1
(PD-L1) expression in colorectal cancer (CRC) are limited and remain controversial. This …

Objective: We investigated microsatellite instability (MSI) status and programed cell death
ligand 1 (PD-L1) expression as predictors of prognosis and responsiveness to …

Colorectal cancer (CRC) is the third leading cause of cancer-related death worldwide. The
prognosis and overall survival of CRC are known to be significantly correlated with the …

It is unknown as to how liver metastases are correlated with host immune status in colorectal
cancer. In this study, we found that IL6, a proinflammatory cytokine produced in tumor …

Programmed death ligand 1 (PD-L1) is an immune checkpoint protein; however, emerging
data suggest that tumor cell PD-L1 may regulate immune-independent and intrinsic cellular …

Introduction The programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1)
axis plays an important role in controlling immune suppression by down-regulating T effector …

The current standard-of-care for metastatic colorectal cancer (mCRC) includes
chemotherapy and anti-angiogenic or anti-epidermal growth factor receptor (EGFR) …

Purpose The prognostic role of programmed death-ligand 1 (PD-L1) in colorectal cancer
remains unclear. We employed a meta-analysis to explore the prognostic value of PD-L1 …

Neuroendocrine tumors (NETs) originate from the neuroendocrine cell system in the
bronchial and gastrointestinal tract and can produce hormones leading to distinct clinical …