Diabetes mellitus (DM) ranks among the severest global health concerns of the 21st century.
It encompasses a group of chronic disorders characterized by a dysregulated glucose …

Developmental biology has advanced the understanding of the intricate and dynamic
processes involved in the formation of an organism from a single cell. However, many gaps …

Treatment of glioblastoma, the most common and aggressive type of primary brain tumors, is
a major medical challenge and the development of new alternatives requires simple yet …

Microcontact printing (µCP) is a commonly used technique for patterning proteins of interest
on substrates. The cells take the shape of these printed patterns. This technique is used to …

Cardiovascular disease (CVD) is among the leading causes of mortality worldwide. The
shortage of donor hearts to treat end-stage heart failure patients is a critical problem. An …

In vitro models of the small intestine are crucial tools for the prediction of drug absorption.
The Caco-2 monolayer transwell model has been widely employed to assess drug …

Although monolayer cell culture models are considered as gold standard for in vitro
modeling of pathophysiological events, they cannot reconstruct in vivo like gradient of gases …

Patterned hydrogel films are attractive for the generation of 3D multicellular spheroids, a
new in vitro cell model. Traditional methods for their synthesis, such as photolithography and …

Bioengineering of three-dimensional (3D) cardiac microtissues is broadly needed in basic
biomedical research and clinical therapy. Biofabrication is a method that is used for the …

The development of simple strategies capable of simultaneously producing hydrophilic
surfaces and controlled surface topography is rare in spite of their huge potential for a wide …